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Displaying results 1441 - 1450 of 10000 in total
  1. Drug

    Baricitinib

    go.drugbank.com/drugs/DB11817
    ApprovedInvestigational

    [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with [remdesivir] under the Emergency Use Authorization (EUA) in November 2020,[L22619] the FDA fully approved … [A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe.

    Products: UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET, UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADET
  2. Drug

    Ulipristal

    go.drugbank.com/drugs/DB08867
    ApprovedInvestigational

    evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily debated due to ethical concerns related to abortion (Rosato et … It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor.

    Products: ACETATO DE ULIPRISTAL, Femke 30 mg Filmtablette
  3. Drug

    Conjugated estrogens

    go.drugbank.com/drugs/DB00286
    ApprovedInvestigational

    [T484] The currently approved product of conjugated estrogens was developed by Wyeth Ayerst and FDA approved in 2003.[L5608] … It also presents a large number of unidentified molecules with weak estrogenic activity as well as non-human molecules when it is obtained from pregnant mares urine.

    Mixtures: DUAVIVE 20 mg/0.45 mg modified - release tablets, DUAVİVE 0.45 MG/20 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 TABLETProducts: TABLETS 0.625 MG, PREMARIN TABLET 0.3 mg
  4. Drug

    Caspofungin

    go.drugbank.com/drugs/DB00520
    ApprovedInvestigational

    It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall.

    Synonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans, -3-hydroxy-L-proline cyclic (6-1)-peptideProducts: CASPOFUNGIN EG, AFUNDAS-L 75 MG IV INFUZYON ICIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 FLAKON
  5. Drug

    Enzalutamide

    go.drugbank.com/drugs/DB08899
    ApprovedInvestigational

    [A252667,A252642] Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was initiated in July 2007. … Compared to the average time of 10 to 15 years for a drug to go from pre-clinical to clinical studies, enzalutamide was developed relatively rapidly.[A252667]

    Products: XTANDI 40 MG, XTANDI ® 40 MG
  6. Drug

    Clevidipine

    go.drugbank.com/drugs/DB04920
    ApprovedInvestigational

    Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.

    Products: Cleviprex 0,5 mg/ml Emulsion zur Injektion
  7. Drug

    Cilazapril

    go.drugbank.com/drugs/DB01340
    ApprovedInvestigational

    It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these varieties are available in the United States.

    Mixtures: Inhibace plus 5 mg/12,5 mg - Filmtabletten, ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADETProducts: Inhibace 0,5 mg - Filmtabletten, Inhibace 5 mg - Filmtabletten
  8. Drug

    Chorionic Gonadotropin (Human)

    go.drugbank.com/drugs/DB09126
    ApprovedInvestigationalVet approved

    The alpha sub-unit is essentially identical to the alpha sub­ units of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as to the alpha sub-unit

    Products: Apl Inj 1000 Iu/ml, โฮค็อก(TM)2000
  9. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibio...

    Mixtures: ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADET, CEFAZIME FOR INJECTION 1 g/vialProducts: SEFAVİS 500 MG IM/IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL, Kefazim 500 mg Trockenstechampulle
  10. Drug

    Aldesleukin

    go.drugbank.com/drugs/DB00041
    ApprovedInvestigational

    This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene.

    Synonyms: ILT-101, 125-L-Serine-2-133-interleukin 2Products: Proleukin 18 x 10 6 IE - Pulver zur Herstellung einer Injektions- oder Infusionslösung, PROLEUKIN 18X106 IU/ML STERİL IV LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET