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Displaying results 1441 - 1450 of 8696 in total
  1. Target

    Transferrin receptor

    go.drugbank.com/bio_entities/BE0004850
    TransporterTargetHumans

    May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation … Mediates uptake of NICOL1 into fibroblasts where it may regulate extracellular matrix production (By similarity)

    Polypeptides: Transferrin receptor protein 1, Transferrin receptor protein 2Synonyms: Transferrin receptor 1
  2. Target

    Dopamine receptor

    go.drugbank.com/bio_entities/BE0009376
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:40683247)

    Polypeptides: Dopamine receptor D1, Dopamine receptor D2Synonyms: Dopamine D1 receptor, Dopamine D2 receptor
  3. Drug

    Perboric acid

    go.drugbank.com/drugs/DB13235
    Approved

    [L1113] By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis.[L2764] … Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate.

    Categories: Antiinfectives and Antiseptics for Local Oral Treatment
  4. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    Gimeracil's main role within Teysuno is to prevent the breakdown of [DB00544] (5-FU), which helps to maintin high enough concentrations for sustained effect against cancer cells [L933]. … Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens.

  5. Drug

    Varicella zoster vaccine (live/attenuated)

    go.drugbank.com/drugs/DB10318
    ApprovedInvestigational

    First approved in May 2006 by the Food and Drug Administration, Zostavax was the first vaccine available for the prevention of shingles. … PHN can last for days, months, or even years following resolution of shingles.

    Mixtures: Priorix - Tetra Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung einer InjektionslösungCategories: Antiinfectives for Systemic Use
  6. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox … Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL.

  7. Drug

    Inulin

    go.drugbank.com/drugs/DB00638
    ApprovedInvestigationalNutraceutical

    A starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan. … It has been used in physiologic investigation for determination of the rate of glomerular function.

    Categories: Tests for Renal Function and Ureteral Injuries
  8. Drug

    Trihexyphenidyl

    go.drugbank.com/drugs/DB00376
    ApprovedInvestigational

    [L31843] Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768] … [L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity.

  9. Drug

    Doxylamine

    go.drugbank.com/drugs/DB00366
    ApprovedInvestigationalVet approved

    It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

    Mixtures: Nicold Medicine for Adults, WICK MediNait Erkältungssirup für die NachtCategories: Antihistamines for Systemic Use, Histamine Receptor Antagonists
  10. Drug

    Ferrous bisglycinate

    go.drugbank.com/drugs/DB11210
    Approved

    It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

    Mixtures: Prenate Max, PR Natal 430