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Displaying results 1451 - 1460 of 3601 in total
  1. Drug

    PF-4191834

    go.drugbank.com/drugs/DB11645
    Investigational

    PF-4191834 has been investigated for the basic science of Asthma.

  2. Drug

    PF-07799933

    go.drugbank.com/drugs/DB17489
    Investigational

    PF-07799933 is a BRAF class 2 inhibitor developed by Pfizer.

  3. Drug

    CA-170

    go.drugbank.com/drugs/DB15772
    Investigational

    CA-170 is a selective, small molecule inhibitor of PD-L1.

  4. Drug

    Burosumab

    go.drugbank.com/drugs/DB14012
    ApprovedInvestigational

    Some adults with this condition suffer from persistent, unrelenting discomfort and complications, such as joint pain, impaired mobility, tooth abscesses and hearing loss [L2346].

  5. Drug

    Salsalate

    go.drugbank.com/drugs/DB01399
    ApprovedInvestigational

    In contrast to aspirin, salsalate causes no greater fecal gastrointestinal blood loss than placebo.

  6. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0002715
    TargetEscherichia coli (strain K12)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:10194342, PubMed:8335646).

    Synonyms: OSB synthase
  7. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0004273
    TargetThermobifida fusca (strain YX)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444).

    Synonyms: OSB synthase
  8. Drug

    Bezisterim

    go.drugbank.com/drugs/DB05212
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    MEM 1414

    go.drugbank.com/drugs/DB05888
    Experimental

    MEM 1414 is a PDE4 inhibitor that is being evaluated for the treatment of Alzheimer’s disease. This drug candidate has completed Phase 1 clinical trials. MEM 1414 works by blocking phosphodiesterase, an enzyme that breaks down an importa...

  10. Target

    Lanosterol synthase

    go.drugbank.com/bio_entities/BE0004668
    TargetYeast

    Lanosterol synthase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:2185141, PubMed:8486282). ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a react...

    Synonyms: OSC