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Displaying results 1451 - 1460 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(8:0/8:0/25:0/25:0)

    smpdb.ca/view/SMP0288590
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  2. Drug

    Povidone

    go.drugbank.com/drugs/DB11061
    ApprovedInvestigationalWithdrawn

    Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant … When in complex with iodine, [DB06812] displays antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect, and povidone acts as a carrier [A32988].

    Synonyms: 1-vinyl-2-pyrrolidinone polymer, 1-ethenyl-2-pyrrolidinone homopolymerMixtures: Leader Artificial Tears 15 mL, FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ
  3. Drug

    Ibrutinib

    go.drugbank.com/drugs/DB09053
    ApprovedInvestigational

    It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
  4. Drug

    Enfuvirtide

    go.drugbank.com/drugs/DB00109
    ApprovedInvestigational

    The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells. … Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesProducts: FUZEON POLVO SOLUCION INYECTABLE 90 MG/MI
  5. Drug

    Gadoteridol

    go.drugbank.com/drugs/DB00597
    ApprovedInvestigational

    [A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876] … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions

    Synonyms: gadolinium 2,2',2''-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetateCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Potassium bicarbonate

    go.drugbank.com/drugs/DB11098
    ApprovedInvestigational

    Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. … [L1836] This FDA denomination classifies potassium bicarbonate as a GRAS ingredient.[L1837]

    Mixtures: POT-K 1,56 G EFERVESAN TABLET, 15 ADET, REFCON ADVANCE 100 MG + 20 MG/ML ORAL SÜSPANSIYONProducts: Effer-K 20 mEq Unflavored, Effer-K 20 mEq Orange Cream
  7. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for rehydration, nutrition, and replenishment of electrolytes. … Potassium is an essential nutrient, like [Calcium] and [Magnesium]. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans.

    Synonyms: KMixtures: Mega-vim 75 With Beta-carotene - Tablets, Magnum-75 Vitamin and Mineral Supplement
  8. Drug

    Bilberry

    go.drugbank.com/drugs/DB14235
    ApprovedWithdrawn

    Synonyms: Dried billberry fruit (vaccinium myrtillus l.), European blueberryCategories: Heterocyclic Compounds, 2-Ring, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  9. Drug

    Marstacimab

    go.drugbank.com/drugs/DB17725
    ApprovedInvestigational

    Marstacimab is a human monoclonal immunoglobulin G Type 1 (IgG1) antibody produced by Chinese hamster ovary (CHO) cells by recombinant DNA technology. … [L51803] It is a tissue factor pathway inhibitor (TFPI) antagonist, which is an endogenous anticoagulant.

    Synonyms: Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1-chain), disulfide with human monoclonal pf-06741086 .lambda.-chain, dimerProducts: Hympavzi 150 mg/mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)
  10. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]

    Categories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: PANBESY CAPSULE 15 MG, DUROMINE CAPSULE 15 mg