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Lumacaftor
go.drugbank.com/drugs/DB09280ApprovedInvestigational[A20301] When used in combination with [DB08820] as the fixed dose combination product Orkambi, lumacaftor is specific for the management of CF in patients with delta-F508 mutations as it acts as a protein-folding … Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older.
Prednicarbate
go.drugbank.com/drugs/DB01130ApprovedIt is used in the treatment of inflammatory skin diseases, such as atopic dermatitis. … Prednicarbate is a relatively new topical corticosteroid drug that displays a similar potency as [hydrocortisone].
Calcium threonate
go.drugbank.com/drugs/DB11168ApprovedWithdrawnIt is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. … Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement [A27266].
Pamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigational[A203267] The second generation bisphosphonates are less common as third generation bisphosphonates, such as [ibandronic acid], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming
Patisiran
go.drugbank.com/drugs/DB14582ApprovedIt is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced.
Tozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigationalComirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older.[L41350] … The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer
Alclofenac
go.drugbank.com/drugs/DB13167ApprovedWithdrawnAlclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Odesivimab
go.drugbank.com/drugs/DB15900ApprovedInvestigational[A222078] INMAZEB™, formerly referred to as REGN-EB3, combines the three humanized IgG1κ mAbs Odesivimab (REGN 3471), [Maftivimab] (REGN 3479), and [Atoltivimab] (REGN 3470) in equimolar proportions
Ginkgo biloba
go.drugbank.com/drugs/DB01381ApprovedInvestigationalNutraceuticaldiseases, such as dementia. … [A232384] _Ginkgo biloba_ was investigated in preliminary studies for a variety of therapeutic purposes such as improving cardiovascular health, sexual dysfunction, psychiatric disorders, skin disorders
Anthrax immune globulin human
go.drugbank.com/drugs/DB09057ApprovedInvestigationalAvailable as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracis lethal and … It is administered in combination with appropriate antibiotic therapy as the immunoglobulin itself is not known to have direct antibacterial activity against anthrax bacteria, which otherwise may continue