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Displaying results 1451 - 1460 of 10000 in total
  1. Drug

    Benznidazole

    go.drugbank.com/drugs/DB11989
    ApprovedInvestigational

    Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.

    Categories: Heterocyclic Compounds, 1-RingProducts: ABALEA ®100 MG
  2. Target

    Potassium channel subfamily K member 10

    go.drugbank.com/bio_entities/BE0013513
    TargetHumans

    K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens t...

    Polypeptides: Potassium channel subfamily K member 10
  3. Drug

    Polidocanol

    go.drugbank.com/drugs/DB06811
    ApprovedInvestigational

    Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower

    Mixtures: DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 20 G, KORTOS 27 MG/5 MG SUPOZİTUVAR, 10 ADETProducts: AETHOXYSKLEROL % 0,5 60 MG 30 ML FLAKON, 1 ADET, VARITHENA POLIDOCANOL INJECTABLE FOAM 10MG/ML
  4. Target

    Neuronal acetylcholine receptor subunit alpha-10

    go.drugbank.com/bio_entities/BE0000411
    TargetHumans

    Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits. E...

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-10Synonyms: NACHR alpha-10, Nicotinic acetylcholine receptor subunit alpha-10
  5. Target

    C-X-C motif chemokine 10

    go.drugbank.com/bio_entities/BE0000934
    TargetHumans

    Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (PubMed:...

    Polypeptides: C-X-C motif chemokine 10Synonyms: IP-10, 10 kDa interferon gamma-induced protein
  6. Target

    Solute carrier family 22 member 10

    go.drugbank.com/bio_entities/BE0003652
    TransporterHumans

    Polypeptides: Solute carrier family 22 member 10
  7. Target

    Cytochrome b-c1 complex subunit 10

    go.drugbank.com/bio_entities/BE0003859
    TargetHumans

    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit...

    Polypeptides: Cytochrome b-c1 complex subunit 10Synonyms: Complex III subunit 10
  8. Drug

    Pegcetacoplan

    go.drugbank.com/drugs/DB16694
    ApprovedInvestigational

    [A235000] Pegcetacoplan for subcutaneous use was granted FDA approval on 14 May 2021.

    Products: EMPAVELI® 54 MG/ML SOLUCIÓN INYECTABLE
  9. Drug

    Dornase alfa

    go.drugbank.com/drugs/DB00003
    ApprovedInvestigational

    The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme.

    Categories: Recombinant Human Deoxyribonuclease 1Synonyms: Deoxyribonuclease (human clone 18-1 protein moiety)
  10. Drug

    Belatacept

    go.drugbank.com/drugs/DB06681
    ApprovedInvestigational

    Belatacept is only 2 amino acids different from abatacept (Orencia). FDA approved on June 15, 2011. … Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each.

    Products: NULOJIX ®250 MG/ VIAL POLVO LIOFILIZADO PARA SOLUCION INYECTABLE INTRAVENOSA