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Displaying results 1461 - 1470 of 3601 in total
  1. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0002715
    TargetEscherichia coli (strain K12)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:10194342, PubMed:8335646).

    Synonyms: OSB synthase
  2. Target

    o-succinylbenzoate synthase

    go.drugbank.com/bio_entities/BE0004273
    TargetThermobifida fusca (strain YX)

    Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444).

    Synonyms: OSB synthase
  3. Drug

    Octocrylene

    go.drugbank.com/drugs/DB09535
    Approved

    Octocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. What makes this chemical such a popular additive to sun block, is its ability to neu...

    Mixtures: OS SILKY SUN CUSHION Broad Spectrum SPF 50, OS SILKY SUN CUSHION Broad Spectrum SPF 50
  4. Drug

    Bezisterim

    go.drugbank.com/drugs/DB05212
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    MEM 1414

    go.drugbank.com/drugs/DB05888
    Experimental

    MEM 1414 is a PDE4 inhibitor that is being evaluated for the treatment of Alzheimer’s disease. This drug candidate has completed Phase 1 clinical trials. MEM 1414 works by blocking phosphodiesterase, an enzyme that breaks down an importa...

  6. Target

    Lanosterol synthase

    go.drugbank.com/bio_entities/BE0004668
    TargetYeast

    Lanosterol synthase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:2185141, PubMed:8486282). ERG7 catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a react...

    Synonyms: OSC
  7. Drug

    Pyrazinamide

    go.drugbank.com/drugs/DB00339
    ApprovedInvestigational

    A pyrazine that is used therapeutically as an antitubercular agent.

  8. Drug

    PF-03758309

    go.drugbank.com/drugs/DB11775
    Investigational

    PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.

    Salts: Pf 03758309 Hydrochloride
  9. Indication

    Hypercholesterolemia, Autosomal Dominant

    go.drugbank.com/conditions/DBCOND0037437
    Drugs: Atorvastatin · Bezafibrate · Fenofibric acid · Inclisiran · Rosuvastatin
    Synonyms: LDL receptor disorder, LDL - Low density lipoprotein receptor disorder
  10. Drug

    PF-06273340

    go.drugbank.com/drugs/DB12269
    Investigational

    Pf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects