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Staurosporine
go.drugbank.com/drugs/DB02010ExperimentalAn indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Categories: P-glycoprotein inhibitorsXanthine
go.drugbank.com/drugs/DB02134InvestigationalA purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xa...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesPlatelet Activating Factor
go.drugbank.com/drugs/DB02261ExperimentalCategories: P-glycoprotein inducers, P-glycoprotein substratesColforsin
go.drugbank.com/drugs/DB02587InvestigationalPotent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also...
Categories: P-glycoprotein inhibitorsDigoxigenin
go.drugbank.com/drugs/DB03671ExperimentalDigoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.
Categories: P-glycoprotein substratesBerberine
go.drugbank.com/drugs/DB04115ApprovedInvestigationalWithdrawnAn alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, P-glycoprotein substratesQuercetin
go.drugbank.com/drugs/DB04216InvestigationalQuercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP1A2 Inhibitors9-Deazaguanine
go.drugbank.com/drugs/DB04356ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesN-Methyl-N-(Methylbenzyl)Formamide
go.drugbank.com/drugs/DB04379ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates