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Displaying results 1461 - 1470 of 5300 in total
  1. Drug

    Oxymetazoline

    go.drugbank.com/drugs/DB00935
    ApprovedInvestigational

    Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … [L15062] As an effective decongestant, oxymetazoline is available in over-the-counter intranasal sprays used to relieve nasal and sinus congestion caused by a wide variety of conditions, such as common

    Products: Rx Act Nasal Sinus, Rx Act Nasal Original
  2. Drug

    WX-554

    go.drugbank.com/drugs/DB21749
    Investigational

    WX-554 is under investigation in clinical trial NCT01581060 (Phase I/​II Dose-escalation Study to Investigate Safety and Pharmacokinetics/​ Pharmacodynamics of WX-554 in Patients With Solid Tumours).

  3. Drug

    Lutropin alfa

    go.drugbank.com/drugs/DB00044
    ApprovedInvestigational

    Its pharmacological action mimics the biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and the development of the corpous luteum.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  4. Drug

    Conjugated estrogens

    go.drugbank.com/drugs/DB00286
    ApprovedInvestigational

    The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  5. Drug

    Eldecalcitol

    go.drugbank.com/drugs/DB05295
    Investigational

    Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis.

  6. Target

    Gentamicin 3-N-acetyltransferase

    go.drugbank.com/bio_entities/BE0001953
    TargetPseudomonas aeruginosa

    Responsible for gentamicin resistance and has a limited substrate range.

    Synonyms: AAC(3)-I
  7. Drug

    PX-102

    go.drugbank.com/drugs/DB15416
    Investigational

    PX-102 is under investigation in clinical trial NCT01998672 (Multiple Ascending Oral Dose Phase I Study With Px-102).

  8. Drug

    Yohimbine

    go.drugbank.com/drugs/DB01392
    ApprovedInvestigationalVet approvedWithdrawn

    It is also alleged to be an aphrodisiac.

    Categories: Genito Urinary System and Sex HormonesInternational brands: Baron-X
  9. Drug

    Paltusotine

    go.drugbank.com/drugs/DB16277
    ApprovedInvestigational

    Paltusotine is a selective somatostatin receptor agonist: It mimics the biological actions of endogenous somatostatin, which activates the somatostatin 2 receptor (SST2) to block the secretion of growth hormone (GH) and decreases the pro...

  10. Drug

    Alclofenac

    go.drugbank.com/drugs/DB13167
    ApprovedWithdrawn

    Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.