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Displaying results 1471 - 1480 of 2483 in total
  1. Drug

    Vandetanib

    go.drugbank.com/drugs/DB05294
    ApprovedInvestigational

    Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. On April 6 2011, vandetanib was approved by the FDA to treat nonresectabl...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  2. Drug

    Palovarotene

    go.drugbank.com/drugs/DB05467
    Approved

    [A244920] The ossification occurring as a result of FOP is insidious and cumulative and is provoked during flare-ups or in response to injury. … Treatment options for patients with FOP are extremely limited, although there has been substantial recent interest in novel treatments for this disease.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
  3. Drug

    Telaprevir

    go.drugbank.com/drugs/DB05521
    ApprovedWithdrawn

    Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  4. Drug

    9-Deazaguanine

    go.drugbank.com/drugs/DB04356
    Experimental

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    N-Methyl-N-(Methylbenzyl)Formamide

    go.drugbank.com/drugs/DB04379
    Experimental

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates
  6. Drug

    Chloramphenicol succinate

    go.drugbank.com/drugs/DB07565
    Approved

    Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. C...

    Categories: P-glycoprotein substrates, P-glycoprotein substrates with a Narrow Therapeutic Index
  7. Drug

    Capravirine

    go.drugbank.com/drugs/DB08502
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  8. Drug

    Isoliquiritigenin

    go.drugbank.com/drugs/DB03285
    Experimental

    Isoliquiritigenin is a precursor to several flavonones in many plants.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  9. Drug

    Azidocillin

    go.drugbank.com/drugs/DB08795
    Experimental

    Azidocillin is a penicillin antibiotic similir to ampicillin.

  10. Drug

    Sulfamoxole

    go.drugbank.com/drugs/DB08798
    Experimental

    Sulfamoxole is an antibacterial in the sulfonamide class.

    Synonyms: 2-(p-Aminobenzenesulfonamido)-4,5-dimethyloxazole, 2-(p-Aminobenzolsulfonamido)-4,5-dimethyloxazolCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors