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AVN-944
go.drugbank.com/drugs/DB05500InvestigationalAVN944 has been associated with cancer cell death in clinical trials. It is being investigated for the treatment of patients with advanced hematologic malignancies. … AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism
Phenformin
go.drugbank.com/drugs/DB00914ApprovedWithdrawnAlthough it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries.
Categories: Drugs Used in DiabetesPegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigationalPegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. … [L50537] Pegulicianine (under the brand name Lumisight) was approved for use by the FDA in April 2024.[L50537,L50547] It received Fast Track and priority review for this indication.[L50547]
Categories: Compounds used in a research, industrial, or household settingLithium carbonate
go.drugbank.com/drugs/DB14509ApprovedInvestigationalThough it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Mixtures: BIOGROW MINIndigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigational[A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to aid in visualizing ureter integrity in cystoscopic assessments.[L42600] … This compound is an acid-base indicator and is used in the production of food colorants and pH tests.
Categories: Compounds used in a research, industrial, or household settingReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalPatients often experience persistent or exacerbating symptoms overtime despite conventional first-line therapies available. … In addition, a significant improvement in lung function was seen, as measured by the volume of air exhaled by patients in one second [L1133].
Faropenem medoxomil
go.drugbank.com/drugs/DB05659InvestigationalFaropenem medoxomil is a broad-spectrum antibiotic that is highly resistant to beta-lactamase degradation. It is being developed jointly by Replidyne, Inc. and Forest Laboratories, Inc. … Faropenem medoxomil is an ester prodrug derivative of the beta-lactam antibiotic [faropenem].
Sarecycline
go.drugbank.com/drugs/DB12035ApprovedInvestigationalSubsequently, while a number of first line tetracycline therapies like doxycycline and minocycline do exist for treating acne vulgaris, sarecycline presents a new and innovative therapy choice because … s Seysara (sarecylcine) as a new first in class narrow spectrum tetracycline derived oral antibiotic for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients
Polyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedPolyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. … PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.
Categories: Compounds used in a research, industrial, or household settingAdemetionine
go.drugbank.com/drugs/DB00118ApprovedInvestigationalNutraceuticalPhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. … It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Mixtures: HEPASELAMİN AMİNOASİT IV İNFÜZYON ÇÖZELTİSİ 500 ML SETLİ ŞİŞE, HEPASELAMİN AMİNOASİT IV İNFÜZYON ÇÖZELTİSİ 500 ML SETSİZ ŞİŞE