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Lubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalA prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. … Lubiprostone is a medication used in the management of idiopathic chronic constipation.
Categories: Prostaglandins EDioxybenzone
go.drugbank.com/drugs/DB11221ApprovedWithdrawnDioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525]. … Dioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays.
Aspergillus fumigatus
go.drugbank.com/drugs/DB10425ApprovedAspergillus fumigatus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureCochliobolus sativus
go.drugbank.com/drugs/DB10433ApprovedCochliobolus sativus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureGadodiamide
go.drugbank.com/drugs/DB00225ApprovedInvestigationalGadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels. … [A263096] Approved by the FDA in 1993, gadodiamide is the first non-ionic GBCA to be used.
Categories: Compounds used in a research, industrial, or household settingProducts: OMNISCAN INJECTION 0.5MMOL/ML-10ML IN GLASS VIAL, OMNISCAN INJECTION 0.5MMOL/ML-20ML IN GLASS VIALPadeliporfin
go.drugbank.com/drugs/DB15575ApprovedInvestigational[A244699] Padeliporfin was first approved by the European Commission on November 10, 2017, for the treatment of low-risk prostate cancer in adults meeting certain clinical criteria.[L39799]
Categories: Sensitizers Used in Photodynamic/radiation TherapyInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalCompared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced with aspartic acid. … This substitution decreases its propensity to form hexamers and gives it a higher rate of absorption following subcutaneous administration compared to native insulin.
Categories: Drugs Used in DiabetesProducts: NovoRapid FlexPen 100U/ml solution for injection in pre-filled pen, RYZODEG® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/mlGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120] … [L8123] Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and calcium ion concentrations.
Synonyms: 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamideCategories: Drugs Used in DiabetesIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[L33204] Isoprenaline was granted FDA approval on 19 February 1948.[L33155] … Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-Isopropylnoradrenaline, N-IsopropylnorepinephrinePiflufolastat F 18
go.drugbank.com/drugs/DB14805ApprovedInvestigationalProstate cancer is the most common non-cutaneous malignancy affecting men in North America[A235344] - despite this, an ongoing challenge in prostate cancer therapy is the difficulty in imaging the extent … levels roughly 1000-fold greater than elsewhere in the body, and even higher in prostate cancer tissue.