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Caspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans, -3-hydroxy-L-proline cyclic (6-1)-peptideGallamine triethiodide
go.drugbank.com/drugs/DB00483ApprovedWithdrawnIt should be used cautiously in patients at risk from increased heart rate but may be preferred for patients with bradycardia. (From AMA Drug Evaluations Annual, 1992, p198) … The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac
Synonyms: Trietioduro de galamina, Triéthiodure de GallamineProducts: Flaxedil Inj 20mg/mlRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigational[A222398] Remdesivir (GS-5734) is an adenosine triphosphate analogue first described in the literature in 2016 as a potential treatment for Ebola. … [L39640] Remdesivir in combination with [baricitinib] for the treatment of COVID-19, was granted an FDA Emergency Use Authorization on November 19, 2020.[L22619]
Categories: MATE 1 Inhibitors, P-glycoprotein substratesProducts: VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL, VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADETPantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedPantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. … Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer.
Mixtures: Multi II IV Vi Tab, Vc IICategories: Preparations for Treatment of Wounds and Ulcers, Vitamin B ComplexZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalZolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … Research also shows that zolpidem is rapid and effective in restoring brain function for patients in a vegetative state following brain injury.
Synonyms: N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamideMixtures: Gabazolpidem-5, Sentrazolpidem PM-5Delorazepam
go.drugbank.com/drugs/DB01511IllicitInvestigationalIn addition to be long acting, delorazepam is relatively potent, with 1 mg of delorazepam being the equivalent of 10 mg diazepam. It has been approved for marketing in Italy. … It is a long acting benzodiazepine which makes it superior in this sense to lorazepam which is short acting. Lorazepam is also a major active metabolite of delorazepam.
Categories: Heterocyclic Compounds, 2-RingInternational brands: ENCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalThe relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. … Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory
Mixtures: PARACETAMOLO E CODEINA DOC GENERICI, Codar DCategories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeHuman varicella-zoster immune globulin
go.drugbank.com/drugs/DB11621ApprovedInvestigationalThe therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus. … It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the disease severity in high-risk patients who
Synonyms: Human herpesvirus 3 immune globulinProducts: Varicella Zoster Immune Globulin InjTafluprost
go.drugbank.com/drugs/DB08819ApprovedChemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: Saflutan 15 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis, SAFLUTAN®Milk thistle
go.drugbank.com/drugs/DB14375ApprovedInvestigationalMilk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Fruit of Silybum Marianum, Milkthistle Fruit (Silybum Marianum L. Gaertner)Products: Dr. Super Khan