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Displaying results 141 - 150 of 158651 in total
  1. Drug

    Euflavine

    go.drugbank.com/drugs/DB13326
    Investigational

    Synonyms: 3,6-diamino-10-methylacridinium chlorideCategories: Antiseptics and Disinfectants, Heterocyclic Compounds, 3-Ring
  2. Drug

    Emtricitabine

    go.drugbank.com/drugs/DB00879
    ApprovedInvestigational

    Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection … in high risk adolescents and adults.

    Mixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, DESCOVY (200/10 MG)Categories: MATE 1 Substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Talbutal

    go.drugbank.com/drugs/DB00306
    ApprovedIllicit

    Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.

    Categories: Heterocyclic Compounds, 1-Ring, Hypnotics and SedativesSynonyms: (RS)-5-allyl-5-sec-butylpyrimidine-2,4,6(1H,3H,5H)-trione, 5-allyl-5-sec-butylbarbituric acid
  4. Drug

    Cyproheptadine

    go.drugbank.com/drugs/DB00434
    ApprovedInvestigational

    Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. … [L32474] It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and its off-label use in the treatment of serotonin syndrome.

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine, 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
  5. Drug

    Capecitabine

    go.drugbank.com/drugs/DB01101
    ApprovedInvestigational

    Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers.

    Categories: Heterocyclic Compounds, 1-Ring, Fluorouracil and prodrugsSynonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
  6. Drug

    Acetazolamide

    go.drugbank.com/drugs/DB00819
    ApprovedInvestigationalVet approved

    (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) … It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual

    Categories: Heterocyclic Compounds, 1-Ring, Antiglaucoma Preparations and MioticsSynonyms: 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide, 5-acetamido-1,3,4-thiadiazole-2-sulfonamide
  7. Drug

    5'-Fluoro-5'-Deoxyadenosine

    go.drugbank.com/drugs/DB03716
    Experimental

    Categories: Heterocyclic Compounds, 2-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: 5'-Fluoro-5'-Deoxyadenosine
  8. Drug

    MK-8777

    go.drugbank.com/drugs/DB18904
    Investigational

    MK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder … (174001/P05704/MK-8777-001)).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5H,7H-PYRIDO(3,2-F)PYRROLO(2,1-C)(1,4)OXAZEPIN-5-ONE, 8,9,9A,10-TETRAHYDRO-, (9AS)-
  9. Drug

    Pyrimethamine

    go.drugbank.com/drugs/DB00205
    ApprovedInvestigationalVet approved

    One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

    Mixtures: SULFADOXINA 500 MG + PIRIMETAMINA 25 MG TABLETASCategories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-Ring
  10. Drug

    Daunorubicin

    go.drugbank.com/drugs/DB00694
    ApprovedInvestigational

    A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.

    Categories: cytarabine and daunorubicin, Anthracyclines and Related SubstancesSynonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione, Leukaemomycin C