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Displaying results 141 - 150 of 10000 in total
  1. Drug

    Benzthiazide

    go.drugbank.com/drugs/DB00562
    Approved

    They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide
  2. Drug

    Leukotriene C4

    go.drugbank.com/drugs/DB08855
    Experimental

    The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produ...

    Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycineCategories: SRS-A
  3. Drug

    Cyproheptadine

    go.drugbank.com/drugs/DB00434
    ApprovedInvestigational

    Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor AntagonistsSynonyms: 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine, 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
  4. Drug

    N-[(E)-3-[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitrobenzamide

    go.drugbank.com/drugs/DB03907
    Experimental

    Synonyms: N-[(E)-3-[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]prop-2-enyl]-2,3-dihydroxy-5-nitrobenzamide
  5. Drug

    Fumaric acid

    go.drugbank.com/drugs/DB01677
    Investigational

    Synonyms: (E)-2-butenedioic acid, (2E)-2-butenedioic acid
  6. Drug

    Butylidenephthalide

    go.drugbank.com/drugs/DB17259
    Experimental

    Synonyms: N-butylidenephthalide, (e)+(z), 1(3h)-isobenzofuranone, 3-butylidene-
  7. Drug

    Leukotriene D4

    go.drugbank.com/drugs/DB11858
    Investigational

    Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis.

    Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine, S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycineCategories: SRS-A
  8. Drug

    Inupadenant

    go.drugbank.com/drugs/DB19129
    Investigational

    Inupadenant is under investigation in clinical trial NCT05060432 (Study of EOS-448 With Standard of Care And/or Investigational Therapies in Participants With Advanced Solid Tumors).

    Synonyms: (+)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-((s)-methanesulfinyl)ethoxy)phenyl)piperazin-1- yl)ethyl)-8-(furan-2-yl)thiazolo(5,4-e)(1,2,4)triazolo(1,5-c)pyrimidin-2(3h)-one, Thiazolo(5,4-e)(1,2,4)triazolo(1,5-c)pyrimidin-2(3h)-one, 5-amino-3-(2-(4-(2,4-difluoro-5-(2-((s)-methylsulfinyl)ethoxy)phenyl)-1-piperazinyl)ethyl)-8-(2-furanyl)-
  9. Drug

    Idronoxil

    go.drugbank.com/drugs/DB04915
    Investigational

    Idronoxil is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Haginin E, (+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-ol
  10. Drug

    NM-004

    go.drugbank.com/drugs/DB18066
    Experimental

    Synonyms: 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid, Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)-