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Oxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A797] Due to this chemical moiety, oxaliplatin readily undergoes non-enzymatic biotransformation, thus complicating oxaliplatin's pharmacokinetics. … [A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination.
Categories: OCT2 Substrates with a Narrow Therapeutic IndexProducts: AL OXA ® SOLUCION CONCENTRADA PARA INFUSION, PLOXAL-S 150 MG/30 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON,1 ADETSugammadex
go.drugbank.com/drugs/DB06206ApprovedInvestigationalSugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery.
Categories: Compounds used in a research, industrial, or household settingProducts: SUGAMMADEX DR. REDDY'S, SUDEX (Sugammadex (as Sodium) Solution for Injection 100mg/ml)alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003Approved= 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120]. … , males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males
Mixtures: Vitamin E 400 Iu and Selenium 25 Mcg Capsules, . & Selenium 50 Mcg CapsulesCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesPrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approvedA synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersProducts: Nu-prednisone, Rectodelt 100 mg ZäpfchenBarium sulfate
go.drugbank.com/drugs/DB11150ApprovedIt is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1957]. This drug is used as a contrast agent in diagnostic x-ray procedures. … Barium sulfate is an inorganic compound with the chemical formula BaSO4 [L1957]. Barium sulfate occurs in nature as the mineral _barite_.
Categories: Compounds used in a research, industrial, or household settingProducts: BARVİXA 150 G/240 ML SÜSPANSİYON, Micropaque CT 50 mg/ml Konzentrat für orale SuspensionBenzethonium
go.drugbank.com/drugs/DB11125ApprovedThere is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … Benzethonium was identified as a novel cancer-specific compound by cell-based small-molecule screen [A32298].
Mixtures: Dr. NumbProducts: Handi-San, finipil Lait 50Iomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigationalIomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use. … [A265090,A265095] Iomeprol first appeared in the market in 1994 [A265095] and is currently used in various diagnostic processes involving x-ray imaging and computed tomography (CT) scans.[L52260]
Categories: Compounds used in a research, industrial, or household settingProducts: IOMERON 350 INJECTION 350 mg/ml, IOMERON 150 100 ML FLAKONSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigational[A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names. … [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im ScCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational[A18262] This is beneficial in the treatment of ADHD as DA activation in the subcortical NA and striatum is associated with many stimulant-associated side effects and an increase in abuse potential, which … [A178090] Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: Ag-atomoxetine, ATOMOXETIN AL 10MG HKPCefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Mixtures: BIGCEF 250/125 MG FILM KAPLI TABLET, 10 ADET, BIGCEF 500/125 MG FILM KAPLI TABLET, 10 ADETProducts: Nu-cefuroxime, Cefuroxim Dr. Eberth 1500 mg Pulver zur Herstellung einer Injektions-/Infusionslösung