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Pralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedPralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after...
Products: Protopam Chloride - (pws 1g/vial)Bleomycin
go.drugbank.com/drugs/DB00290ApprovedInvestigationalA complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is...
Products: BLEOMICINA 15 U VIAL, DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vialCapreomycin
go.drugbank.com/drugs/DB00314ApprovedInvestigationalCyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus.
Products: Capastat Pws Im 1g VialSecretin human
go.drugbank.com/drugs/DB09532ApprovedInvestigationalHuman secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH l...
Products: Secretin Inj 75unit/vial, Secretin Iberoinvesa Pharma S.L. 100 CU Pulver und Lösungsmittel zur Herstellung einer Injektions-/InfusionslösungDiclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to infl...
Mixtures: Kapzin DC, Diclofex DCInternational brands: Nu-DicloOxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A797] Due to this chemical moiety, oxaliplatin readily undergoes non-enzymatic biotransformation, thus complicating oxaliplatin's pharmacokinetics. … [A260396] However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair protein to DNA harder compared to cisplatin or carboplatin's adducts, resulting in greater cytotoxic
Products: HOXALIRA®50 MG/VIAL, HOXALIRA® 100 MG/ VIALColistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aer...
Products: COLIJECT ® 150 MG / VIAL, COLISTIMETATO 150MG/VIALEravacycline
go.drugbank.com/drugs/DB12329ApprovedInvestigationalEravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacte...
Products: XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIALIndinavir
go.drugbank.com/drugs/DB00224ApprovedInvestigationalA potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Synonyms: (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamideProducts: RETOR-VIDDactinomycin
go.drugbank.com/drugs/DB00970ApprovedInvestigationalA compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termina...
Synonyms: Actinomycin D, ACTINOMYCIN-DProducts: U. DACTINOMYCIN FOR INJECTION 0.5 mg/vial, ACTINOMICINA D INYECTABLE