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Ceritinib
go.drugbank.com/drugs/DB09063ApprovedInvestigationalresults in constitutive kinase activity that contributes to carcinogenesis and seems to drive the malignant phenotype. … Ceritinib exerts its therapeutic effect by inhibiting autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and proliferation of ALK-dependent cancer cells
Synonyms: N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamideCategories: Antineoplastic and Immunomodulating AgentsLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigational[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.
Mixtures: FEM 7 COMBI 50MCG, CYCLO PROGYNOVA N 2MG/0.15Categories: levonorgestrel and estrogen, levonorgestrel and estrogenBotrytis cinerea
go.drugbank.com/drugs/DB10428ApprovedBotrytis cinerea is a fungus which can provoke allergic reactions. Botrytis cinerea extract is used in allergenic testing.
Products: Molds, Rusts and Smuts, Botrytis cinereaProbenecid
go.drugbank.com/drugs/DB01032ApprovedInvestigationalProbenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate.
Synonyms: 4-(N,N-Dipropylsulfamoyl)benzoesäure, 4-(Di-n-propylsulfamoyl)benzoesäureMixtures: Probenecid and Colchicine, Probenecid and ColchicineTrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalTrandolapril may be used to treat mild to moderate hypertension, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, as an adjunct treatment … for congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
Mixtures: TARKA 180MG/2MG, TARKA 180MG/2MGCategories: trandolapril and verapamil, ACE Inhibitors and Calcium Channel BlockersAngioedema and urticaria
go.drugbank.com/conditions/DBCOND0027508Drugs: CyproheptadineSynonyms: Urticaria and angioedema, Angioedema and urticariaSaquinavir
go.drugbank.com/drugs/DB01232ApprovedInvestigationalIn 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a relatively benign adverse effect profile as compared … Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection.
Categories: Metabolic Side Effects of Drugs and SubstancesProducts: Invirase - Cap 200mg, BIOQUINAVIR ® CAPSULAS 200MGFusarium oxysporum vasinfectum
go.drugbank.com/drugs/DB10435ApprovedFusarium oxysporum vasinfectum is a fungus which can provoke allergic reactions. Fusarium oxysporum vasinfectum extract is used in allergenic testing.
Products: Molds, Rusts and Smuts, Fusarium vasinfectumEgg white
go.drugbank.com/drugs/DB10528ApprovedEgg white allergenic extract is used in allergenic testing.
Products: Food - Animal Products and Poultry Products, Egg, White Gallus sp.Nabumetone
go.drugbank.com/drugs/DB00461ApprovedNabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval in December, 1991.[L6568] … [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action.
Mixtures: NuDroxiPAK N-500Categories: Antiinflammatory and Antirheumatic Products, Antiinflammatory and Antirheumatic Products, Non-Steroids