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Ropinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPINIROL-NEURAX 5 MG, ROPINIROL AL 5 MG FILMTABLBromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnBromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. … In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological lactation after finding that bromocriptine was not shown to be safe for use.
Categories: Serotonin 5-HT2 Receptor Agonists, Cytochrome P-450 SubstratesProducts: PARLODEL 5 MG YAVAŞ SALIMLI KAPSÜL, 28 ADET, GYNODEL 2.5 MG TABLET, 30 ADETMorinamide
go.drugbank.com/drugs/DB13417InvestigationalProducts: MORFOZID 500 MG TABLET, 50 ADET, MORFOZID 500 MG TABLET, 500 ADETFlumethasone
go.drugbank.com/drugs/DB00663ApprovedVet approvedAs it is a privalate salt, its anti-inflammatory action is concentrated at the site of application.
Mixtures: LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalSulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditi...
Synonyms: cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid, (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acidProducts: CLINORIL 200 MG TABLETAS, Sulindac-150 Tab 150mgIobenguane
go.drugbank.com/drugs/DB06704ApprovedInvestigationalSynthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cycl...
Synonyms: m-iodobenzylguanidineProducts: MON.MIBG-131I-TANI 9-120 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 120 MBQ/ML, MON.MIBG-131I-TANI 9-120 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 37 MBQ/MLLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigational[A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsProducts: LETROL 2.5 MG FILM TABLET, 30 ADET, LETROKABI 2.5 MG FILM TABLET, 30 ADETAgomelatine
go.drugbank.com/drugs/DB06594ApprovedInvestigationalAgomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. … Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsProducts: VALDOXAN 25 MG, VALDOXAN® 25 MGTiclopidine
go.drugbank.com/drugs/DB00208ApprovedTiclopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: TACRON TABLET 250 mg, TICLID 250 MG TABLET, 30 ADETEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalThe sodium salt has been also used to treat primary pulmonary hypertension.
Synonyms: (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidProducts: VELETRI® 1.5 MG, VELETRI®0.5 MG