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Displaying results 1501 - 1510 of 10000 in total
  1. Pathway

    Bafetinib Inhibition of BCR-ABL Action Pathway

    smpdb.ca/view/SMP0031699
    Drug action

    Bafetinib is a tyrosine kinase inhibitor used to treat chronic myelogenous leukemia (CML), a cancer characterized by increased and unregulated growth of white blood cells in the bone marrow and the accumulation of these cells in the bloo...

    Drugs: Bafetinib
    Enzymes: S-phase kinase-associated protein 2
  2. Pathway

    Non-Ketotic Hyperglycinemia

    smpdb.ca/view/SMP0125580
    Disease

    Non Ketotic Hyperglycinemeia (Glycine encephalopathy; Glycine cleavage system deficiency; NKH) is caused by mutations in several genes in the mitochondrial glycine cleavage system. These include the genes encoding P protein (GLDC), T pro...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  3. Drug

    Bifenthrin

    go.drugbank.com/drugs/DB15056
    Experimental

    Bifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry).

  4. Drug

    Dipotassium phosphate

    go.drugbank.com/drugs/DB09414
    ApprovedInvestigational

    Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.

    Mixtures: BİOFLEKS İZOLEKS-S pH 7,4 IV İNFÜZYONLUK ÇÖZELTİ, 500 ML (PVC TORBA) SETLİ, BİOFLEKS İZOLEKS-S pH 7,4 IV İNFÜZYONLUK ÇÖZELTİ, 1000 ML (PVC TORBA) SETLİCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Droxidopa

    go.drugbank.com/drugs/DB06262
    ApprovedInvestigational

    Europe. … Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S.

    Categories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsSynonyms: L-DOPS, L-Dihydroxyphenylserine
  6. Drug

    Anecortave

    go.drugbank.com/drugs/DB12081
    Experimental

    Anecortave is under investigation in clinical trial NCT00691717 (Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension).

  7. Drug

    Setogepram

    go.drugbank.com/drugs/DB15447
    Investigational

    Setogepram is under investigation in clinical trial NCT03184584 (Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome).

    Synonyms: 2-(3-Pentylphenyl)acetic acid, 3-Pentylbenzenacetic acid
  8. Drug

    YCT-529

    go.drugbank.com/drugs/DB21748
    Investigational

    YCT-529 is under investigation in clinical trial NCT06542237 (Open Label, Repeat Dose Study Evaluating YCT-529 in Healthy Males).

  9. Pathway

    Glycine and Serine Metabolism

    smpdb.ca/view/SMP0000004
    Metabolic

    This pathway describes the synthesis and breakdown of several small amino acids, including glycine, serine, and cysteine. All of these compounds share common intermediates and almost all can be biosynthesized from one another. Serine and...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  10. Pathway

    Dihydropyrimidine Dehydrogenase Deficiency (DHPD)

    smpdb.ca/view/SMP0000179
    Disease

    Dihydropyrimidine Dehydrogenase Deficiency (DHPD; Thymine-uraciluria) is a rare autosomal recessive disorder caused by a mutation in the DPYD gene which codes for dihydropyrimidine dehydrogenase. A deficiency in this enzyme results in ac...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1