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Magnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: Clinimix E, Clinimix ETetrofosmin
go.drugbank.com/drugs/DB11180ApprovedTetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. … Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788]
Selegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedIt may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. … (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigationalSparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub … [L51419] Sparsentan was initially developed for the treatment of hypertension;[A257340] however, it has shown to be efficient in the reduction of proteinuria in patients with IgAN and focal segmental glomerulosclerosis
Categories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor BlockerInositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnIt is associated with reduced flushing compared to other vasodilators by being broken down into the metabolites and inositol at a slower rate. … Inositol nicotinate is prescribed in Europe under the name Hexopal as a symptomatic treatment for severe intermittent claudication and Raynaud’s phenomenon.
Mixtures: TL-Care DHAPhenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalDuring the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract. … Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis.
Mixtures: EGOPSORYL TA GEL, EGOPSORYL TA GELUrofollitropin
go.drugbank.com/drugs/DB00094ApprovedVet approvedWithdrawnUrofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF). … The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: BRAVELLE 75 IU SC ENJEKSIYON ÇÖZELTI IÇEREN FLAKON VE ÇÖZÜCÜ IÇEREN AMPUL, 5 ADET, BRAVELLE 75 IU SC ENJEKSIYON ÇÖZELTI IÇEREN FLAKON VE ÇÖZÜCÜ IÇEREN AMPUL, 10 ADETDextrose, unspecified form
go.drugbank.com/drugs/DB09341ApprovedInvestigationalVet approvedIt is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. … Glucose is listed on the World Health Organization's List of Essential Medicines.
Mixtures: Clinimix E, Clinimix EOmburtamab
go.drugbank.com/drugs/DB15635Investigational[A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers.
Zolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigationalZolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine. … [A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor Agonists