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Displaying results 1511 - 1520 of 10000 in total
  1. Drug

    Asenapine

    go.drugbank.com/drugs/DB06216
    ApprovedInvestigational

    Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with

    Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin 5-HT1 Receptor Antagonists
  2. Drug

    Netupitant

    go.drugbank.com/drugs/DB09048
    ApprovedInvestigational

    Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai Inc. and Helsinn Therapeutics (U.S.) Inc. under the brand Akynzeo.

    Synonyms: 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]propanamideCategories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 Antagonists
  3. Drug

    Cetuximab

    go.drugbank.com/drugs/DB00002
    ApprovedInvestigational

    Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor … [A227973] EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible for regulating epithelial tissue development and homeostasis.

    Categories: Epidermal Growth Factor Receptor Antagonist, EGFR (Epidermal Growth Factor Receptor) inhibitorsProducts: ERBITUX ® 5 MG/ML, ERBITUX® 5 MG/ML
  4. Drug

    Tolnaftate

    go.drugbank.com/drugs/DB00525
    ApprovedVet approved

    Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.

    Mixtures: PERMUT®, เดอมิกซ์-4Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester
  5. Drug

    Inotersen

    go.drugbank.com/drugs/DB14713
    ApprovedInvestigational

    Hereditary transthyretin amyloidosis is caused by single-nucleotide variants in the gene encoding transthyretin (TTR), which lead to transthyretin misfolding and the deposition of amyloid substance systemically … Inotersen is a transthyretin-directed antisense oligonucleotide for the treatment of the polyneuropathy caused by hereditary transthyretin-mediated amyloidosis in adults.

  6. Drug

    Cefiderocol

    go.drugbank.com/drugs/DB14879
    ApprovedInvestigational

    [A189150] A concern noted in the trial was a 0.3% higher rate of all cause mortality, the cause of which has not been determined. … Cefiderocol is a cephalosporin antibacterial drug and exerts a mechanism of action similar to other β-lactam antibiotics.

    Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting
  7. Drug

    Loracarbef

    go.drugbank.com/drugs/DB00447
    ApprovedWithdrawn

    Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Plecanatide

    go.drugbank.com/drugs/DB13170
    ApprovedInvestigational

    Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC).

    Categories: Guanylate Cyclase-C Agonist, Guanylyl Cyclase C Agonists
  9. Drug

    Alcloxa

    go.drugbank.com/drugs/DB11205
    Approved

    Mixtures: Dr.LORD Green Propol Tooth
  10. Drug

    Dienestrol

    go.drugbank.com/drugs/DB00890
    ApprovedWithdrawn

    Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. … Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy.

    Synonyms: 4,4'-Hydroxy-γ,δ-diphenyl-β,δ-hexadiene, p,p'-(Diethylideneethylene)diphenol