Search
Aripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors. … [L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.[L6136]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ABILIFY 5 MG, Arileto 10 mg-TablettenCrotamiton
go.drugbank.com/drugs/DB00265ApprovedCrotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor.
Categories: Compounds used in a research, industrial, or household settingToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalThe proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance. … of T-cell proliferation and cytokine production, and thus its overexpression can inhibit T-cell-mediated immune surveillance of tumors.
Cyclacillin
go.drugbank.com/drugs/DB01000ApprovedA cyclohexylamido analog of penicillanic acid.
Categories: combinations of penicillinsCorifollitropin alfa
go.drugbank.com/drugs/DB09066ApprovedInvestigationalrisk of ovarian hyperstimulation in the high responder study group of women [L2276], [A32526]. … The increased in the number of eggs retrieved under corifollitropin alfa regimen represents the elevated effectiveness of this drug, however, warns at the same time against the possibility of an increased
Categories: Sex Hormones and Modulators of the Genital SystemThymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigational[A274683, A274688] As of now, its primary role is in research and as a sensitizer or modulator in experimental chemotherapy regimens, rather than a standalone, approved therapeutic agent. … Thymidine is a naturally occurring deoxyribonucleoside that is a crucial component of the DNA salvage pathway and a building block for DNA synthesis.
Iohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIts low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingProducts: OMNIPAQUE (300 MG I/ML), OMNIPAQUE (350 MG I/ML)Glofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigational, after two or more lines of systemic therapy under accelerated approval based on response rate and durability of response. … ) after two or more lines of systemic therapy.
Apomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigational[A203597,A203618] Apomorphine was granted FDA approval on 20 April 2004.[L13919] … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.
Categories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diolGepirone
go.drugbank.com/drugs/DB12184Approvedside effects as that of the placebo. … Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and post-synaptic 5HT<sub>1A</sub> receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome