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Corticorelin ovine triflutate
go.drugbank.com/drugs/DB09067ApprovedIt provides a differential diagnosis for Cushing's disease (a pituitary source of ACTH excess) or of ectopic ACTH syndrome (an ectopic source of ACTH excess). … If corticorelin injection results in an increase of plasma ACTH and cortisol, the patient is diagnosed with Cushing's disease.
Tapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalTapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. … The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.
Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCalfactant
go.drugbank.com/drugs/DB06415ApprovedInvestigationalIt is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. … Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation.
Synonyms: SF-RI 1Products: ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADETCinpanemab
go.drugbank.com/drugs/DB16127InvestigationalCinpanemab is under investigation in clinical trial NCT03318523 (Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's Disease).
Synonyms: lambda, anti-(homo sapiens alpha-synuclein)humanized monoclonal antibody.gamma.1 heavy chain (1-442) (homo sapiens vh (ighv3-25*03 (86%) (ighd)-ighj2*01) (8.10.4) (1-113)-homo sapiens ighg1*03 (ch3(k107>del, Immunoglobulin g1-lambda, anti-(homo sapiens snca (synuclein alpha, alpha-synuclein, park1, park4, parkinson disease (autosomal dominant, lewy body) 4, non a4 component of amyloid precursor, nacp)), monoclonalBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion.
Mixtures: BENADRYL WET COUGH, GLICERTOX N FProducts: ROMITOX NF ADULTOS, ROMITOX NF PEDIATRICOPemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalgrowth factor receptor 2 (FGFR2) gene fusion or other rearrangements as detected by an FDA-approved test. … [A198984] Deregulated FGFR signalling pathway can lead the development of oncogenes and tumour-promoting physiological processes, such as cancer cell proliferation, enhanced angiogenesis, and evasion of
Technetium Tc-99m tetrofosmin
go.drugbank.com/drugs/DB09160ApprovedIt is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit which yields an injection. … Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsTafluprost
go.drugbank.com/drugs/DB08819ApprovedA prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. … Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Products: SAFLUTAN 15 MCG/ML TEK DOZLUK GOZ DAMLASI, 30 ADETCannabidiol
go.drugbank.com/drugs/DB09061ApprovedInvestigationalThis can be achieved through heating, smoking, vaporization, or baking of dried unfertilized female cannabis flowers. … In particular, CBD has shown promise as an analgesic, anticonvulsant, muscle relaxant, anxiolytic, antipsychotic and has shown neuroprotective, anti-inflammatory, and antioxidant activity, among other
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeVotucalis
go.drugbank.com/drugs/DB05032InvestigationalrEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.