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Dolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigational[A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. … [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Categories: Antivirals used in combination for the treatment of HIV infectionsIvacaftor
go.drugbank.com/drugs/DB08820ApprovedInvestigational, an ion channel involved in the transport of chloride and sodium ions across cell membranes. … Alterations in the CFTR gene result in altered production, misfolding, or function of the protein and consequently abnormal fluid and ion transport across cell membranes.
Synonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamideInfluenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15515ApprovedInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mixtures: Influvac Tetra, suspension for injection in pre-filled syringe, INFLUVAC TETRA, SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MLRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalRisedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. … It functions by preventing resorption of bone[FDA Label][A959].
Mixtures: RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 4 ADET, RISEPLUS D3 35 MG/2800 IU EFERVESAN TABLET, 12 ADETStreptococcus pneumoniae type 33f capsular polysaccharide antigen
go.drugbank.com/drugs/DB10341ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia. … Streptococcus pneumoniae type 33f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 33f of *Streptococcus pneumoniae
Mixtures: PNEUMOVAX 23 Injektionslösung in einer Fertigspritze, PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche4-(Isopropylamino)diphenylamine
go.drugbank.com/drugs/DB14195Approved4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N-Fenyl-N'-isopropyl-p-fenylendiamin, 1,4-Benzenediamine, N-(1-methylethyl)-N'-phenyl-HGS-TR2J
go.drugbank.com/drugs/DB05895ExperimentalHGS-TR2J is a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies. … It is developed by Human Genome Sciences, Inc and is under Phase I of clinical trial.
Pioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. … [A19759] Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due to the presence of multiple adverse effects and warnings regarding their use (e.g. congestive heart
Categories: Drugs Used in DiabetesProducts: PIO - LN 15, PIO - LN 30Polihexanide
go.drugbank.com/drugs/DB12277ApprovedInvestigational[L53003] It was initially approved in August of 2024, and is the first and only approved therapy to treat patients with _Acanthamoeba_ keratitis. [L53143] … [A1351,A273908] Polihexanide is approved in Europe under the name Akantior for the treatment of _Acanthamoeba_ keratitis, an ocular infection caused by the _Acanthamoeba_ parasite.
Categories: Compounds used in a research, industrial, or household settingHydroxyethyl cellulose
go.drugbank.com/drugs/DB11602ApprovedIt is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic … It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature.
Categories: Compounds used in a research, industrial, or household setting