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Trastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalTrastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Second that there is a black box warning of serious side effects such as hepatotoxicity, embryo-fetal toxicity, and cardiac toxicity.
Synonyms: T-DM1Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexTicarcillin
go.drugbank.com/drugs/DB01607ApprovedVet approvedWithdrawnAn antibiotic derived from penicillin similar to carbenicillin in action.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, α-carboxy-3-thienylmethylpenicillinPhenoxymethylpenicillin
go.drugbank.com/drugs/DB00417ApprovedInvestigationalVet approvedPhenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK.[A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin]. … Phenoxymethylpenicillin has also be used in some cases as prophylaxis against susceptible organisms.
Categories: Penicillin G, Heterocyclic Compounds, 1-RingSynonyms: (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidNiacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Synonyms: Vitamin B-3, 3-carboxypyridineMixtures: BION 3 FILM COATED TABLET, Vc IICefoxitin
go.drugbank.com/drugs/DB01331ApprovedInvestigationalCefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by <i>Streptomyces lactamdurans</i>.
Synonyms: (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidCategories: Heterocyclic Compounds, 2-RingThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnA barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. … It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure.
Synonyms: 2-Thio-5-ethyl-5-sec-pentylbarbituric acid, 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dioneCategories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesHypophosphatemia
go.drugbank.com/conditions/DBCOND0023801Drugs: 1,6-Fructose Diphosphate (Linear Form) · Burosumab · Fosfructose · Sodium phosphate, dibasic · Sodium phosphate, monobasicSynonyms: Reduction in phosphorus, Decreases in phosphorusSincalide
go.drugbank.com/drugs/DB09142ApprovedSincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders. … Naturally occurring cholecystokinin is a gastrointestinal peptide hormone normally essential for stimulating protein and fat digestion in the body.
Synonyms: CCK-8, CCK C-terminal octapeptideProducts: Kinevac Pws Inj 5mcg/vialParicalcitol
go.drugbank.com/drugs/DB00910ApprovedInvestigationalParicalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. … Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesProducts: PARICAVER 5 MCG/1 ML IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, DEPARIC 5 MCG/ML IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADETAnal Fistulas
go.drugbank.com/conditions/DBCOND0043885Drugs: EsculinSynonyms: Fistula-in-ano, Fistula in Ano