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Displaying results 1561 - 1570 of 10000 in total
  1. Drug

    Chlorine dioxide

    go.drugbank.com/drugs/DB12453
    Approved

    Chlorine Dioxide has been used in trials studying the treatment of Halitosis.

    Categories: Compounds used in a research, industrial, or household settingProducts: Pure O2-S F, Pure O2 S
  2. Drug

    Rimantadine

    go.drugbank.com/drugs/DB00478
    Approved

    An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.

    Synonyms: alpha-Methyl-1-adamantanemethylamineCategories: Influenza A M2 Protein Inhibitor
  3. Drug

    Pacritinib

    go.drugbank.com/drugs/DB11697
    ApprovedInvestigational

    [L40793] Approximately 50% of patients with primary MF have a mutation of the _JAK2_ gene, which is also commonly mutated in patients with polycythemia vera or essential thrombocythemia. … of both primary and secondary MF in patients with platelet counts < 50 x 10<sup>9</sup>/L.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP1A2 Inducers
  4. Drug

    RTP-801i

    go.drugbank.com/drugs/DB06048
    Investigational

    RTP-801i is an siRNA drug candidate designed to inhibit the expression of the hypoxia-inducible gene RTP801.

  5. Drug

    Talazoparib

    go.drugbank.com/drugs/DB11760
    ApprovedInvestigational

    Talazoparib is an inhibitor of mammalian polyadenosine 5’-diphosphoribose polymerases (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and DNA repair.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substrates
  6. Drug

    Chorionic Gonadotropin (Human)

    go.drugbank.com/drugs/DB09126
    ApprovedInvestigationalVet approved

    HCG is composed of an alpha and a beta sub-unit. … As a drug product, chorionic gonadotropin is a highly purified pyrogen-free preparation obtained from the urine of pregnant females.

    Synonyms: h-HCGProducts: PREGNYL 5000IE PLI 3X(1+1), MERIONAL® 75 UI
  7. Drug

    Fluciclovine (18F)

    go.drugbank.com/drugs/DB13146
    ApprovedInvestigational

    Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging.

    Synonyms: (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid, Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid
  8. Drug

    Yttrium Y-90

    go.drugbank.com/drugs/DB13076
    ApprovedInvestigational

    Yttrium 90 has been investigated for the treatment of Colon Cancer and Colorectal Cancer.

    Synonyms: Y-90, Yttrium Y 90
  9. Drug

    Paramethadione

    go.drugbank.com/drugs/DB00617
    Approved

    Paramethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  10. Drug

    Biperiden

    go.drugbank.com/drugs/DB00810
    ApprovedInvestigationalWithdrawn

    A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. … It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol, alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol