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PF-06751979
go.drugbank.com/drugs/DB15105InvestigationalPF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).
Categories: Heterocyclic Compounds, 1-RingSurufatinib
go.drugbank.com/drugs/DB15106InvestigationalSurufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTipranavir C-14
go.drugbank.com/drugs/DB15108InvestigationalTipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).
Synonyms: Tipranavir C-14Categories: Heterocyclic Compounds, 1-RingAcetic acid C-11
go.drugbank.com/drugs/DB15111InvestigationalAcetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and
Synonyms: Acetic acid C-11Vamorolone
go.drugbank.com/drugs/DB15114ApprovedInvestigationalVamorolone is a novel and fully synthetic glucocorticoid developed by Santhera Pharmaceuticals. … [L48671,L48676] In December 2023, it was approved in the EU for the treatment of patients ≥4 years of age.[L49505]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersRamatercept
go.drugbank.com/drugs/DB15116InvestigationalRamatercept is under investigation in clinical trial NCT00952887 (A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 in Healthy Postmenopausal Women).
Ropeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life. … Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a
Synonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bCategories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsGSK-239512
go.drugbank.com/drugs/DB15120InvestigationalGSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
Categories: Heterocyclic Compounds, 2-RingCaficrestat
go.drugbank.com/drugs/DB15121InvestigationalAT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDorzagliatin
go.drugbank.com/drugs/DB15123InvestigationalDorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
Categories: Heterocyclic Compounds, 1-Ring