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Vitamin D
go.drugbank.com/drugs/DB11094ApprovedInvestigationalNutraceuticalVet approvedVitamin D ultimately comprises a group of lipid-soluble secosteroids responsible for a variety of biological effects, some of which include increasing the intestinal absorption of calcium, magnesium, and phosphate. With reference to huma...
Mixtures: Ch-P CapCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLight green SF yellowish
go.drugbank.com/drugs/DB11183ApprovedLight green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exi...
Categories: P-glycoprotein inhibitorsEvening primrose oil
go.drugbank.com/drugs/DB11358ApprovedNutraceuticalEvening primrose oil comes from the extraction from Oenothera biennis seeds and it is commonly used as an alternative source for omega-6 essential fatty acids. In its composition it presents some fatty acids such as DB00132 and DB13854. ...
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 Enzyme InhibitorsCarbomycin
go.drugbank.com/drugs/DB11383ExperimentalVet approvedCarbomycin, also called magnamycin, is crystalline macrolide antibiotic. This antibacterial is obtained from Streptomyces halstedii and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains. The...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsEprinomectin
go.drugbank.com/drugs/DB11405ExperimentalVet approvedCategories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsPimavanserin
go.drugbank.com/drugs/DB05316ApprovedInvestigationalPimavanserin is an atypical antipsychotic indicated for the treatment of psychiatric disorders. Although the exact mechanism of action is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesApremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalApremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesLumateperone
go.drugbank.com/drugs/DB06077ApprovedInvestigationalSchizophrenia is a complex mental illness and impacts approximately 1% of the population. Although there are several antipsychotics including aripiprazole, paliperidone and clozapine available for clinical use, they are generally accompa...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGarenoxacin
go.drugbank.com/drugs/DB06160ExperimentalGarenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors