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Levoketoconazole
go.drugbank.com/drugs/DB05667Approved[A244078, A244083] [Ketoconazole] has been used both on- and off-label to treat CS due to its ability to inhibit cortisol production. … It possesses most of the inhibitory effect towards steroidogenic enzymes, making it an attractive candidate for CS treatment with a potentially lower toxicity profile than its racemate.
Categories: Corticosteroids for Systemic UseMethicillin Resistant Staphylococcus Aureus Infection (MRSA)
go.drugbank.com/conditions/DBCOND0115216Synonyms: Bacterial infection due to unspecified staphylococcus, Infection due to Methicillin resistant Staphylococcus aureusUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigational[A244210, A244215,A241045] Ublituximab was initially developed by LFB Group but was licensed to TG Therapeutics in 2012. … [A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity and ability to clear bound cells through mechanisms such as antibody-dependent cellular cytotoxicity
Soft Tissue Sarcoma
go.drugbank.com/conditions/DBCOND0029966Synonyms: Sarcoma, no International Classification of Diseases for Oncology subtypeNonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalIt is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. … Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa).
Categories: Compounds used in a research, industrial, or household settingSquamous Cell Carcinoma In-situ (SCC-is)
go.drugbank.com/conditions/DBCOND0043487Drugs: Aminolevulinic acidSynonyms: Squamous cell carcinoma, no International Classification of Diseases for Oncology subtype, Squamous cell carcinoma in situ, no International Classification of Diseases for Oncology subtypeProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy.
Categories: Hormonal Contraceptives for Systemic UseIdebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalDue to its biochemical mode of action, it's thought that idebenone may re-activate viable-but-inactive retinal ganglion cells (RGCs) in LHON patients [L885]. … It is not currently approved for use by either the Food and Drug Administration (USA) or Health Canada.
Categories: Psychostimulants, Agents Used for ADHD and Nootropics, Compounds used in a research, industrial, or household settingSchistosomiasis [Bilharziasis]
go.drugbank.com/conditions/DBCOND0031620Drugs: PraziquantelSynonyms: Disease due to Schistosomatidae (disorder)Aspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSION