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Displaying results 1581 - 1590 of 10000 in total
  1. Drug

    Pegfilgrastim

    go.drugbank.com/drugs/DB00019
    ApprovedInvestigational

    Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, [filgrastim]. … [L9779,L9785,L43050] These biosimilars are highly similar to the reference product, Neulasta, in terms of pharmacological and pharmacokinetic profile and conditions of use.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: PEG-G-CSF, Pegylated G-CSF
  2. Drug

    Acetazolamide

    go.drugbank.com/drugs/DB00819
    ApprovedInvestigationalVet approved

    However, its usefulness is transient often because of rapid development of tolerance. … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

    Categories: combinations of sulfonamidesProducts: ACETAZOLAMIDA 250 MG, Diamox 250 mg - Tabletten
  3. Drug

    Olive oil

    go.drugbank.com/drugs/DB09567
    ApprovedInvestigational

    Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. … Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].

    Mixtures: Numeta G 13 % E Emulsion zur Infusion, Numeta G 16 % E Emulsion zur Infusion
  4. Drug

    Fedratinib

    go.drugbank.com/drugs/DB12500
    ApprovedInvestigational

    [A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090]

    Categories: combinations of sulfonamidesProducts: Inrebic 100 mg capsules, Inrebic 100 mg Sert Kapsül, 120 ADET
  5. Drug

    Lurbinectedin

    go.drugbank.com/drugs/DB12674
    ApprovedInvestigational

    [L14336] This accelerated approval is based on the rate and duration of therapeutic response observed in ongoing clinical trials and is contingent on the verification of these results in confirmatory trials … the substitution of the tetrahydroisoquinoline with a tetrahydro β‐carboline that results in increased antitumour activity of lurbinectedin as compared to its predecessor.

  6. Drug

    Mebanazine

    go.drugbank.com/drugs/DB09248
    ApprovedWithdrawn

    Mebanazine, also known as _Actomol_, is a monoamine oxidase inhibitor (MAOI) belonging to the _hydrazine_ class of chemicals. … It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  7. Drug

    Edrophonium

    go.drugbank.com/drugs/DB01010
    Approved

    A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Ospemifene

    go.drugbank.com/drugs/DB04938
    Approved

    FDA approved on February 26, 2013. … Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause

    Categories: Sex Hormones and Modulators of the Genital System
  9. Drug

    Iodamide

    go.drugbank.com/drugs/DB08948
    ApprovedWithdrawn

    Iodamide is a contrast medium molecule that is no longer marketed in the United States.

    Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household setting
  10. Drug

    Eugenol

    go.drugbank.com/drugs/DB09086
    ApprovedInvestigational

    There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache. … Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction.

    Categories: Compounds used in a research, industrial, or household setting