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Calusterone
go.drugbank.com/drugs/DB01564ExperimentalIllicitA 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.
Synonyms: 17-beta-Hydroxy-7-beta,17-alpha-dimethylandrost-4-ene-3-one, 17beta-Hydroxy-7beta,17-dimethylandrost-4-en-3-oneMephentermine
go.drugbank.com/drugs/DB01365ApprovedWithdrawnAlthough the central stimulant effects of mephentermine are much less than those of amphetamine, its use may lead to amphetamine-type dependence. … A sympathomimetic agent with mainly indirect effects on adrenergic receptors. It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia.
Categories: Adrenergic alpha-1 Receptor AgonistsZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalZuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. … These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsSynonyms: (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanolUblituximab
go.drugbank.com/drugs/DB11850ApprovedInvestigationalCD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions. … (ADCC), mediated by interactions between an antibody and Fcγ receptors on natural killer cells or macrophages.
Categories: Leukemia, Lymphocytic, Chronic, B-Cell, drug therapyLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalThis higher proportion of T3 in desiccated thyroid products can lead to supraphysiologic levels of T3 which may put patients at risk of thyrotoxicosis if thyroid extract therapy is not adjusted according … [A179935] As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular resistance are closely linked to thyroid status.
Mixtures: L THYROX JOD HEXAL 50/150, L THYROX JOD HEXAL 50/150Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 InhibitorsSomatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawnProsomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 (SST-28), an extended SST-14 sequence to the N-terminus [A20384]. … [DB00104] is a long-acting analogue of somatostatin that inhibits the release of a number of hormones, and is clinically used to relieve symptoms of uncommon gastroenteropancreatic endocrine tumours, as
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL, DELT-SOMAT®Danaparoid
go.drugbank.com/drugs/DB06754ApprovedWithdrawnDanaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans [A32565]. … Danaproid is used in the treatment of heparin-induced thrombocytopenia (HIT) as an off-label indication and prevention of post-operative deep venous thrombosis (DVT).
Human calcitonin
go.drugbank.com/drugs/DB06773Approved[A32098] It is used as an alternative for people developing antibodies against salmon calcitonin.[A32100] … Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.
Cysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigational[L15606,L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and require frequent treatment with eye drops, typically every waking hour. … Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome.
Synonyms: 2-amino-1-ethanethiol, β-MEAProducts: CYSTAGON ® 150 MG, CYSTAGON ® 50 MG CAPSULASCurcuma xanthorrhiza oil
go.drugbank.com/drugs/DB11265ApprovedNutraceutical_Curcuma xanthorrhiza_ oil is found as an active ingredient in cosmetic and hygienic products, and marketing of products containing _Curcuma xanthorrhiza_ oil is authorized in some European countries including … _Curcuma xanthorrhiza_ oil is comprised of 1-2% of curcumin and 3-12% volatile oil, which mainly contains sesquiterpenes, 44.5% of xanthorrhizol, and a small amount of [DB01744] [F114].