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Mephentermine is a sympathomimetic agent used in the treatment of hypotension. A sympathomimetic agent with mainly indirect effects on adrenergic receptors.
- Mechanism
- Curator reviewed
Mephentermine is an alpha adrenergic receptor agonist, but also acts indirectly by releasing endogenous norepinephrine. Cardiac output and systolic and diastolic pressures are usually increased. A change in heart rate is variable, depending on the degree of vagal tone. Sometimes the net vascular effect may be vasodilation. Large doses may depress the myocardium or produce central nervous system (CNS) effects.
- Primary indication
- Used to maintain blood pressure in hypotensive states.Curator reviewed
- Formula / weight
- C11H17N · 163.2594 g/mol (avg)
- First approval
- Canada, 1994
- Code names
- WY-585
Resolves to
RXQCGGRTAILOIN-UHFFFAOYSA-NSMILESCNC(C)(C)CC1=CC=CC=C1What you can answer from here — as of September 12, 2026
Which drugs share a target with Mephentermine, and which of those have an active Phase 3 trial?