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Displaying results 1581 - 1590 of 10000 in total
  1. Drug

    7-methyl-5'-guanylic acid

    go.drugbank.com/drugs/DB03593
    Experimental

    Categories: RNA Caps, RNA, Messenger
  2. Drug

    Posizolid

    go.drugbank.com/drugs/DB04850
    Investigational

    no results were reported). … Posizolid (AZD2563) is an oxazolidinone antibiotic.

  3. Drug

    Tioconazole

    go.drugbank.com/drugs/DB01007
    Approved

    Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. … In addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.[L50166]

  4. Drug

    Epicept NP-1

    go.drugbank.com/drugs/DB05492
    Investigational

    EpiCept NP-1 Cream is a patented formulation containing two FDA-approved drugs, amitriptyline (a widely-used antidepressant) and ketamine (an NMDA antagonist that is used as an anesthetic). … EpiCept NP-1 is a prescription topical analgesic cream designed to provide effective, long-term relief from the pain of peripheral neuropathies.

    Synonyms: Epicept NP-1
  5. Drug

    Potassium gluconate

    go.drugbank.com/drugs/DB13620
    Approved

    Potassium gluconate is a salt of [DB01345] and is classified as a food additive by the FDA [L2654]. It is also used as a potassium supplement [L2657]. Potassium is an essential nutrient. … It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining cell function [A32222].

  6. Drug

    Vorasidenib

    go.drugbank.com/drugs/DB17097
    ApprovedInvestigational

    Vorasidenib is a first-in-class dual isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor. … [A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms.

    Synonyms: 1,3,5-triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-n2,n4-bis((1r)-2,2,2-trifluoro-1-methylethyl)-
  7. Drug

    Tirzepatide

    go.drugbank.com/drugs/DB15171
    ApprovedInvestigational

    [A246260] Tirzepatide comprises a 39 amino acid linear synthetic peptide conjugated to a C20 fatty diacid moiety. … Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.

  8. Drug

    Hydroxystilbamidine

    go.drugbank.com/drugs/DB14753
    Approved

    Hydroxystilbamidine isethionate is used in the therapy of some patients with nonprogressive blastomycosis of the skin, and pulmonary or systemic blastomycosis in children, with fewer side effects than amphotericin B. Hydroxystilbamidine ...

  9. Drug

    Ladarixin

    go.drugbank.com/drugs/DB16212
    Investigational

    Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).

    Categories: Receptors, Interleukin-8A, antagonists & inhibitors
  10. Drug

    Anthrax vaccine

    go.drugbank.com/drugs/DB11003
    ApprovedInvestigational

    It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis which are grown in a chemically defined protein-free medium. … [L47526] It is considered one of the most likely agents to be used in a biological attack.