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Diclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).[L7360] … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling.
Mixtures: CODEFEN 50/50 MG EFERVESAN TABLET, 20 ADET, MEGAFLEX 50/8 MG MR KAPSÜL, 14 KAPSÜLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesLacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigationalAs a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008.
Mixtures: ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADET, ELEPSİ 50 MG+100 MG TEDAVİYE BAŞLAMA PAKETİ, 42 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPhenoxymethylpenicillin
go.drugbank.com/drugs/DB00417ApprovedInvestigationalVet approvedPhenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK.[A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin]. … An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by penicillin G-sensitive microorganisms
Categories: Penicillin G, Heterocyclic Compounds, 1-RingSynonyms: (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidCarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigationalCarbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled. … Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus.
Mixtures: TUSSYL® MIEL JARABE, AXIM TOSTHERAPY FORTE®Synonyms: (L)-2-Amino-3-(carboxymethylthio)propionic acid, (R)-S-(carboxymethyl)cysteineLincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approved[A190621] Clinical use of lincomycin has largely been superseded by its semisynthetic derivative [clindamycin] due to its higher efficacy and a wider range of susceptible organisms, though lincomycin remains … [A190657, A190621] Lincomycin was approved by the FDA on December 29, 1964.[L33214]
Categories: Heterocyclic Compounds, 1-RingProducts: LINCOFECT - 250, LINOSIN 600 MG/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 50 AMPULCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, a...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideSennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalThe medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label]. … Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase
Salts: Sennosides A and BMixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg EachSodium bicarbonate
go.drugbank.com/drugs/DB01390ApprovedInvestigationalSodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Mixtures: PRONAT 500 mg+267 mg+160 mg/10 ml ORAL SÜSPANSIYON, 200 ML, GASVİN 500 MG + 267 MG + 160 MG / 10 ML SÜSPANSİYON, 200 MLProducts: NURSE BABY 50 MG/5 ML ORAL ÇÖZELTİ, 10 ADET, Bio-sidoz 1000 mg Gastro Rezistan Tablet, 50 ADETFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigational(From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis.
Mixtures: Fusicutan 20 mg/g + 1 mg/g Creme, Fucibet Lipid 20 mg/g + 1 mg/g CremeCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigationalNitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins.
Mixtures: NITROGLICERINA 0.1 MG/ML EN DEXTROSA 5% SOLUCION INYECTABLE, Nitroglycerin In 5% Dextrose Inj.-400mcg/mlCategories: Compounds used in a research, industrial, or household setting