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Human immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIntravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and io...
Products: INTRAGAM P, BERIGLOBINA - PPenpulimab
go.drugbank.com/drugs/DB16747ApprovedInvestigational[A273848] In order to further reduce the risk of toxicities and improve efficacy, penpulimab was designed with Fc mutations in order to eliminate Fc receptor and complement-mediated effector function, … Penpulimab is a humanized monoclonal IgG1 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1).
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is...
Mixtures: Prascion FCProducts: Pharmassist Clarifex Ph Mud Crm 3.0%Carboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalCarboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or t...
Mixtures: Refresh Digital PF, Refresh RELIEVA PFProducts: FREEGEN PFMethylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigationalA177541] There is a dose-related effect of psychostimulants on receptor stimulation, where higher doses are shown to increase norepinephrine (NE) and dopamine (DA) efflux throughout the brain which can result
Products: Jornay PM, JORNAY PM Extended-ReleaseUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Products: YouGreen F, Umecta PD UreaNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsOlanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigationalOlanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent. Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and has a methyl group attached to the piperazine ring. Th...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Ag-olanzapine Fc, Jamp Olanzapine FcTicagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigationalTicagrelor, or AZD6140, was first described in the literature in 2003. Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilin...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Trixevas 90mg FC TabletAmino acids
go.drugbank.com/drugs/DB09393InvestigationalMixture of amino acids ; used for parenteral nutrition in infants.
Products: F HBC, F 040