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Displaying results 151 - 160 of 35530 in total
  1. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    [A235860,A235865] A meta-analysis of over 145,000 patients showed the risk of stroke in patients taking atenolol may depend on the age of the patient. … [A235865] The use of atenolol may need to be based on more patient factors than hypertension alone.[A235850,A235855,A235860,A235865]

    Synonyms: 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol, 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamideMixtures: NIF TEN 50, NIF-TEN CAPSULE
  2. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.

    Synonyms: (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-olMixtures: Van-dorzolamide-timolol, KRYTANTEK OFTENO® LIBRE DE CONSERVADORES
  3. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). … As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.

    Synonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  4. Drug

    Isosorbide dinitrate

    go.drugbank.com/drugs/DB00883
    ApprovedInvestigational

    A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.

    Synonyms: Dinitrato de isosorbida, D-Isosorbide dinitrateCategories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  5. Drug

    Ethanolamine oleate

    go.drugbank.com/drugs/DB06689
    Approved

    Ethanolamine oleate is a mild sclerosing agent. … It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.

    Synonyms: Oleate de monoethanolamine, Oleato de monoetanolaminioCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Ambroxol

    go.drugbank.com/drugs/DB06742
    ApprovedInvestigational

    The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important … Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

    Synonyms: Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)-, N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanolMixtures: ULAX-C, BROGAL T
  7. Drug

    Hydroxocobalamin

    go.drugbank.com/drugs/DB00200
    ApprovedInvestigational

    Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.

    Synonyms: Vitamin B-12bMixtures: TRIBEDOCE C/L, ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5)
  8. Drug

    Miconazole

    go.drugbank.com/drugs/DB01110
    ApprovedInvestigationalVet approved

    Despite having been in clinical use for an extended period, resistance to miconazole among susceptible organisms is relatively low.[A203636] … [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream.

    Synonyms: 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole, 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazoleInternational brands: Femizol-M
  9. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine

    Synonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol, (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diolCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  10. Drug

    Clonidine

    go.drugbank.com/drugs/DB00575
    ApprovedInvestigational

    Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. … [L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]

    Synonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine, 2-((2,6-Dichlorophenyl)imino)imidazolidineCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index