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Chlorpromazine
go.drugbank.com/drugs/DB00477ApprovedInvestigationalVet approvedChlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Synonyms: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amineCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.
Mixtures: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg, Implicor 50 mg/5 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigational[L8657,L8660,L8663,L8666,L8669] Medroxyprogesterone acetate was granted FDA approval on 18 June 1959.[L8657]
International brands: Depo-subq provera 104Mixtures: DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET, DIVICONT TABLETAS 1 MG/5 MGNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigational[A35203] It was developed by Bristol Myers Squibb.[L12129] Nivolumab was granted FDA approval on 22 December 2014. … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.
Categories: Immunoglobulin GProducts: OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML, OPDIVO 100 INF. IÇIN KONS. IÇEREN FLAKON, 1 ADETZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: COMBİVİR 150 MG/300 MG FİLM KAPLI TABLET, LAMIVUDINA 150 MG & ZIDOVUDINA 300 MG TABLETASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]
Products: LILCARLIL® 10 MG/ML (150 MG/15ML), CARBOPLATINO 50 MG/5 MLPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalPaliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug.
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsProducts: @ctavis 50 mg Depot-Injektionssuspension, @ctavis 100 mg Depot-InjektionssuspensionRifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnThe parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid. … [A39990] Rifamycin has had several direct derivative products such as rifamycin SV, rifaximin, rifampin and rifamycin CV.
Mixtures: RIFOCIN 250 MG+10 MG/3 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 100 ADET, RIFETEM 250 MG / 3 ML AMPUL, 50 ADETCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A2 InhibitorsDarbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Products: ARANESP 100 UG, NESP INJECTION PLASTIC SYRINGE 10 mcg/0.5mlAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalIt is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.
Mixtures: Innoprax-5Categories: M2 Protein Inhibitors, Influenza A M2 Protein Inhibitor