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Triethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigationaltolerant to [penicillamine]. … [A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and
Citric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedCitric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. … The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Mixtures: IDkit HP ONE, Care One Original Antacid and Pain ReliefHydroxyethyl Starch
go.drugbank.com/drugs/DB09106ApprovedInvestigationalHydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. … HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Mirvetuximab soravtansine
go.drugbank.com/drugs/DB12489ApprovedInvestigationaltube, or primary peritoneal cancer who have received 1-3 prior systemic treatment regimens. … [A254392,L43967] DM4 is conjugated to the antibody with a drug-to-antibody ratio of 3.5:1.
Amphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigationalAmphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. … [L5194] During World War II, amphetamine was used to promote wakefulness in the soldiers.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDelamanid
go.drugbank.com/drugs/DB11637ApprovedInvestigationalSpontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 coenzymes responsible for bioactivation of delamanid contributes to this effect [L1407]. … It is marketed by Otsuka Pharmaceutical Co., Ltd (Tokyo, Japan).
Carbon monoxide
go.drugbank.com/drugs/DB11588ApprovedInvestigationalA test of the diffusing capacity of the lungs for carbon monoxide (DLCO), is one of the most clinically valuable tests of lung function testing. … The DLCO measures the ability of the lungs to transfer gas from inhaled air to the red blood cells in pulmonary capillaries. The DLCO test is both convenient and simple for the patient to undergo.
Mixtures: Lung Diffusion Test Mix No Ne Co, Co-NE-O2-N2 MixtureSynonyms: COSelenious acid
go.drugbank.com/drugs/DB11127ApprovedOne study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans. … Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements.
Mixtures: Formula F L W, DAILY-ONE 45 FILM TABLETD-alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14002ApprovedNutraceuticalVet approvedNevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. … Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E.
Mixtures: Obtrex One, Obstetrix ONEErgotamine
go.drugbank.com/drugs/DB00696ApprovedA vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome