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Avatrombopag
go.drugbank.com/drugs/DB11995ApprovedInvestigational[L2932] In July 2025, the FDA expanded approval to include a new pediatric formulation, Doptelet Sprinkle (avatrombopag oral granules), specifically designed for children aged one to less than six years
Ruxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigationalRuxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hemato...
Liraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigationalVictoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine fo...
3-ketoacyl-CoA thiolase
go.drugbank.com/bio_entities/BE0004257TargetPseudomonas fragiCatalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
Synonyms: Fatty acid oxidation complex subunit betaNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
go.drugbank.com/bio_entities/BE0000037TargetHumansEssential for the catalytic activity and assembly of complex I (PubMed:22499348) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor
Synonyms: Complex I-23kDNADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
go.drugbank.com/bio_entities/BE0000093TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-13kD-ANADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
go.drugbank.com/bio_entities/BE0000307TargetEnzymeHumansEssential for the catalytic activity of complex I (PubMed:17275378) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor
Synonyms: Complex I-20kDSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
go.drugbank.com/bio_entities/BE0000176TargetEnzymeHumansFlavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone
Synonyms: Flavoprotein subunit of complex IINADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
go.drugbank.com/bio_entities/BE0000512TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B18Selamectin
go.drugbank.com/drugs/DB11459ExperimentalVet approvedIt also removes 2 types of lungworm in cats and one type of lungworm in dogs. It is distributed by Zoetis, a former Pfizer subsidiary. It is structurally related to ivermectin and milbemycin.