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Displaying results 1591 - 1600 of 8171 in total
  1. Drug

    Lindane

    go.drugbank.com/drugs/DB00431
    ApprovedWithdrawn

    An organochlorine insecticide that has been used as a pediculicide and a scabicide. … Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment.

  2. Drug

    Metenkefalin

    go.drugbank.com/drugs/DB12668
    Investigational

    Metenkefalin is an endogenous opioid and beta-endorphin.[A203225] It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. … [A203210] Metenkefalin, along with [tridecactide], are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]

    Categories: mu-Opioid Receptor Agonist
  3. Drug

    Betamethasone phosphate

    go.drugbank.com/drugs/DB14669
    ApprovedVet approved

    Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium...

    Categories: P-glycoprotein inducers, Cytochrome P-450 CYP3A Inducers
  4. Target

    3-oxoacyl-[acyl-carrier-protein] synthase 1

    go.drugbank.com/bio_entities/BE0000801
    TargetEscherichia coli (strain K12)

    Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor (PubMed:19679654, PubMed:22017312, PubMed:8910376, PubMed:90138...

    Synonyms: KAS I
  5. Drug

    Etoperidone

    go.drugbank.com/drugs/DB09194
    ApprovedWithdrawn

    Etoperidone is an atypical antidepressant introduced in Europe in 1977. … It is a phenylpiperazine-substituted triazole derivative with a composition that classifies it as an analog of tradozone and presents a similar pharmacological profile.

  6. Drug

    Ajmaline

    go.drugbank.com/drugs/DB01426
    ApprovedWithdrawn

    An alkaloid found in the root of Rauwolfia serpentina, among other plant sources.

  7. Drug

    Aluminum oxide

    go.drugbank.com/drugs/DB11342
    ApprovedWithdrawn

    It is considered an indirect additive used in food contact substances by the FDA.

    Mixtures: POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOS
  8. Drug

    Pf-04531083

    go.drugbank.com/drugs/DB12468
    Investigational

    Pf-04531083 has been investigated for the treatment of Pain and Chronic Pain.

  9. Drug

    PF-06835919

    go.drugbank.com/drugs/DB19163
    Investigational

    PF-06835919 is under investigation in clinical trial NCT05463575 (Ketohexokinase Inhibition in NAFLD).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  10. Drug

    Dabrafenib

    go.drugbank.com/drugs/DB08912
    ApprovedInvestigational

    [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955]

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2B6 Inducers