Search
Mediator of RNA polymerase II transcription subunit 1
go.drugbank.com/bio_entities/BE0004382TargetHumansComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the ...
Synonyms: Thyroid receptor-interacting protein 2, Peroxisome proliferator-activated receptor-binding proteinLenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigationalHIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens. Lenacapavir is a first-in-class ...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesNeutral amino acid transporter B(0)
go.drugbank.com/bio_entities/BE0000236TargetTransporterHumansMediates D-serine release from the retinal glia potentially affecting NMDA receptor function in retinal neurons.
Synonyms: Baboon M7 virus receptor, RD114/simian type D retrovirus receptorAcetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigationalAcetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) ...
Mixtures: Fem pH, Acetate Buffer Ph 4.85Deoxyhypusine hydroxylase
go.drugbank.com/bio_entities/BE0018877TargetHumansCatalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-tran...
Synonyms: HEAT-like repeat-containing protein 1CD320 antigen
go.drugbank.com/bio_entities/BE0019797TransporterHumansReceptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213).
Synonyms: Transcobalamin receptorVolume-regulated anion channel subunit LRRC8A
go.drugbank.com/bio_entities/BE0016599TargetHumansEssential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:24725410, PubM...
Synonyms: Leucine-rich repeat-containing protein 8ASteroidogenic factor 1
go.drugbank.com/bio_entities/BE0003359TargetHumansTranscriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues (PubMed:27378692). Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B a...
Synonyms: Steroid hormone receptor Ad4BP, Nuclear receptor subfamily 5 group A member 1Janus (JAK) kinases
go.drugbank.com/bio_entities/BE0027976TargetHumansThe heterodimeric cytokine receptor complexes are composed of (1) a TYK2-associated receptor chain (IFNAR1, IL12RB1, IL10RB or IL13RA1), and (2) a second receptor chain associated either with JAK1 or JAK2 … Involved in the oncostatin-M-mediated signaling pathway through both type I OSM receptor complex (heterodimers composed of LIFR and IL6ST) and type II OSM receptor complex (heterodimers composed of OSMR
Polypeptides: Non-receptor tyrosine-protein kinase TYK2Function: acetylcholine receptor bindingLecithin, soybean
go.drugbank.com/drugs/DB14161InvestigationalA complex mixture of phospholipids; glycolipids; and triglycerides; with substantial amounts of phosphatidylcholines; phosphatidylethanolamines; and phosphatidylinositols, which are sometimes loosely termed as 1,2-diacyl-3-phosphocholine...
Mixtures: GNC PP AA Formula