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Metoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Categories: Adrenergic beta-1 Receptor AntagonistsProducts: Metoprolol Succinate E/r, METOPROLOLINYECCIONBP (1MG/ML)- 5 ML AMPOLLA DE VIDRIOBetrixaban
go.drugbank.com/drugs/DB12364ApprovedBetrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [A7708]. … for VTE [A27285].
Beeswax
go.drugbank.com/drugs/DB11600ApprovedThe wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins. … Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions.
Raloxifene
go.drugbank.com/drugs/DB00481ApprovedInvestigationalDue to the risk of bone fractures that may lead to morbidities and reduced quality of life, the management of osteoporosis in postmenopausal women with the use of therapeutic agents in addition to concurrent … Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and
Categories: Sex Hormones and Modulators of the Genital System, Estrogen Receptor ModulatorsArformoterol
go.drugbank.com/drugs/DB01274ApprovedIt works by relaxing muscles in the airways to improve breathing. … The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients
Categories: Agents to Treat Airway Disease, Adrenergic beta-2 Receptor AgonistsAsparaginase Erwinia chrysanthemi
go.drugbank.com/drugs/DB08886ApprovedInvestigationallymphoma in adult and pediatric patients who are allergic to the _E. coli_-derived asparaginase. … [A236359] Asparaginase _Erwinia chrysanthemi_ was first approved by the FDA in November 2011 to treat patients with acute lymphoblastic leukemia (ALL) who are allergic to _E. coli_-derived asparaginase
Galantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalIt also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance. … [A182993] The drug was approved by the FDA in 2001 for the treatment of mild to moderate dementia of the Alzheimer's type.
Products: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL ® ER CAPSULAS DE 16 MGSynthetic Conjugated Estrogens, B
go.drugbank.com/drugs/DB09318Approvedto be equivalent. … Prior to menopause, the primary source of estrogen is the ovarian follicle, which secretes 70-500 micrograms of estradiol daily, depending on the phase of the menstrual cycle.
Butamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnThe FDA removed all parenteral butamben products from the market, possibly due to the poor solubility of this drug.[A254247,L43942] … Due to its very low water solubility, butamben is considered to be suitable only for topical anesthesia.
Protriptyline
go.drugbank.com/drugs/DB00344ApprovedThe antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … Protriptyline may be used for the treatment of depression.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome