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Doxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigational[A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285] … Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension.
Categories: Drugs Used in Benign Prostatic HypertrophyProducts: Cardura XL, CARDURA XLGenistein
go.drugbank.com/drugs/DB01645InvestigationalIt has been determined to be the active ingredient in <I>Felmingia vestita</I>, which is a plant traditionally used against worms. … It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent.
Mixtures: OSMEGA 600 MG/400 IU/25 MG EFERVESAN TABLET, 30 ADET, CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADETCategories: Compounds used in a research, industrial, or household settingFenfluramine
go.drugbank.com/drugs/DB00574ApprovedIllicitInvestigationalWithdrawnIt is characterized by recurrent pharmacoresistant seizures, which increase in frequency and severity with disease progression. … It is currently sold under the name FINTEPLA® by Zogenix INC.[L14522]
Synonyms: DL-FenfluraminePancrelipase lipase
go.drugbank.com/drugs/DB13147ApprovedInvestigational[L2509] The pancrelipase lipase is an enzyme secreted by the pancreas that is responsible for the hydrolysis of dietary fat molecules in the human digestive system. … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Mixtures: KREON MIKRO 5000 IU MINIMIKROSFER,DaxibotulinumtoxinA
go.drugbank.com/drugs/DB17929ApprovedInvestigational_C. botulinum_ is known to produce toxins that can cause botulism in humans. … It is a botulinum toxin without accessory proteins purified from the bacterium _Clostridium botulinum_ type A,[L47840] the gram-positive anaerobic bacterium primarily present in soil.
Coagulation factor VIIa Recombinant Human
go.drugbank.com/drugs/DB00036ApprovedInvestigationalNovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Categories: Increased Coagulation Factor IX ActivityExagamglogene autotemcel
go.drugbank.com/drugs/DB15572ApprovedInvestigational[L49231] It is the first CRISPR-based gene editing therapy to be approved in the United States. … [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS.
Respiratory syncytial virus vaccine, adjuvanted
go.drugbank.com/drugs/DB17762ApprovedInvestigational[L46352] It was also later approved by Health Canada on August 4, 2023,[L47666] and the EMA in March 2025.[L52380] … It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with
Dostarlimab
go.drugbank.com/drugs/DB15627ApprovedInvestigationalA prospective phase II study in patients with mismatch repair-deficient locally advanced rectal cancer resulted in all twelve patients exhibiting a complete clinical response.[A248905] … Dostarlimab is an IgG<sub>4</sub> humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1).
Foscarbidopa
go.drugbank.com/drugs/DB16171ApprovedFoscarbidopa is under investigation in clinical trial NCT04379050 (Extension Study to Evaluate Safety and Tolerability of 24-hour Daily Exposure of Continuous Subcutaneous Infusion of ABBV-951 in Adult
Mixtures: Produodopa 240 mg/ml + 12 mg/ml Infusionslösung