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Luspatercept
go.drugbank.com/drugs/DB12281ApprovedInvestigationalLuspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1. … [L42455] Luspatercept is novel in that it ameliorates anemia via action on late-stage erythropoiesis, in contrast to typical erythropoiesis-stimulating agents (ESAs), such as [darbepoetin alfa] and [epoetin
Products: Reblozyl 25 mg powder for solution for injection, Reblozyl 75 mg powder for solution for injectionEncorafenib
go.drugbank.com/drugs/DB11718ApprovedInvestigationalBRAF V600E or V600K mutation, as detected by an FDA-approved test. … Encorafenib, also known as _BRAFTOVI_, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: BRAFTOVI® 75 MG CÁPSULAS, BRAFTOVİ 75 MG SERT KAPSÜL, 42 ADETReboxetine
go.drugbank.com/drugs/DB00234ApprovedInvestigationalWithdrawnReboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. … Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: Edronax 4 mg - Tabletten, EDRONAX 4 MG TABLET, 60 ADETChlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalA nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. … Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Synonyms: γ-[p-di(2-chloroethyl)aminophenyl]butyric acid, N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acidProducts: Leukeran 2 mg - Filmtabletten, LEUKERAN 2 MG TABLET, 25 ADETDL-alpha tocopheryl acetate
go.drugbank.com/drugs/DB14477ApprovedMixtures: Tl-hem 150, Tl-hem 150Synonyms: DL-alpha tocopheryl acetate, DL-alpha-tocopheryl acetateUlmus pumila pollen
go.drugbank.com/drugs/DB10362ApprovedUlmus pumila pollen is the pollen of the Ulmus pumila plant. Ulmus pumila pollen is mainly used in allergenic testing.
Mixtures: Western 10 Tree Pollen Mix, Western 10 Tree Pollen MixProducts: Center-AL - Ulmus Pumila PollenDichloroacetic acid
go.drugbank.com/drugs/DB08809ApprovedInvestigationalWithdrawnDCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization and removal of a wide variety of skin and tissue lesions), but was cancelled post market … Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase.
Products: Bichloracetic Acid 100%Medazepam
go.drugbank.com/drugs/DB13437InvestigationalMixtures: TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 40 ADET, TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 20 ADETProducts: NOBRAL 10 MG KAPSÜL, 250 ADET, NOBRAL 10 MG KAPSÜL, 50 ADETPyritinol
go.drugbank.com/drugs/DB13084InvestigationalPyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Products: ENCEFABOL 100 MG, เมโมนอล 100Disulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Antabus 400 mg lösliche Tabletten, ANTABUS 500 MG TABLET, 500 ADET