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Displaying results 1631 - 1640 of 5756 in total
  1. Drug

    Spermidine

    go.drugbank.com/drugs/DB03566
    Investigational

    It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

    Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamine
  2. Drug

    Sipoglitazar

    go.drugbank.com/drugs/DB19312
    Experimental

    Categories: PPAR gamma, agonists
  3. Drug

    Froniglutide

    go.drugbank.com/drugs/DB16178
    Investigational

    Glymera is under investigation in clinical trial NCT01658501 (Phase 2b Multicenter, Randomized, Double-blind, Placebo- and Active-controlled, Parallel-group Study to Assess the PD Response and Safety of

  4. Drug

    Triciribine

    go.drugbank.com/drugs/DB12405
    Investigational

    Triciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative, Breast Adenocarcinoma, and Stage IV Breast Cancer, among others.

  5. Drug

    Tazemetostat

    go.drugbank.com/drugs/DB12887
    ApprovedInvestigational

    Tazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. Tazemetostat was first named in literature as EPZ-6438. Tazemetaostat was granted FDA app...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  6. Drug

    Sulfamethoxazole

    go.drugbank.com/drugs/DB01015
    ApprovedInvestigational

    Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic ac...

    Mixtures: Nu-cotrimox Tab 400/80mg, Nu-cotrimox Sus 40/8mg/mlCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  7. Drug

    Uprosertib

    go.drugbank.com/drugs/DB11969
    Investigational

    Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.

  8. Drug

    Citrulline

    go.drugbank.com/drugs/DB00155
    InvestigationalNutraceutical

    Citrulline is an amino acid. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is deri...

    Synonyms: N5-carbamoylornithine, N5-Carbamoyl-L-ornithine
  9. Drug

    Acetic acid C-11

    go.drugbank.com/drugs/DB15111
    Investigational

    Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and

  10. Drug

    AR-9281

    go.drugbank.com/drugs/DB06345
    Investigational

    AR-9281 inhibits soluble epoxide hydrolase.