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Translocator protein
go.drugbank.com/bio_entities/BE0000736TargetHumansWas initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678)
Synonyms: Mitochondrial benzodiazepine receptor, Peripheral-type benzodiazepine receptorP2Y purinoceptor 14
go.drugbank.com/bio_entities/BE0009825TargetHumansReceptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP
Synonyms: UDP-glucose receptor, G protein-coupled receptor 105Function: G protein-coupled purinergic nucleotide receptor activityEcallantide
go.drugbank.com/drugs/DB05311ApprovedEcallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema. Ecallantide is a recombinant 60-amino-acid protein produced in Pichia pastoris yeast cells ...
Tonapofylline
go.drugbank.com/drugs/DB12569InvestigationalTonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
Categories: Receptor, Adenosine A1ATP-binding cassette sub-family C member 9
go.drugbank.com/bio_entities/BE0000469TargetHumansSubunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (PubMed:9831708). Can form a sulfo...
Synonyms: Sulfonylurea receptor 2Efmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalEfmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It ...
NKG2-D type II integral membrane protein
go.drugbank.com/bio_entities/BE0010415TargetHumansActs as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. … Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected
Synonyms: NK cell receptor D, NKG2-D-activating NK receptorJosamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.