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Diphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalA meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. … When diphenoxylate is used alone, it is classified as a Schedule II.
Phenylketonuria (PKU)
go.drugbank.com/conditions/DBCOND0058086Drugs: PegvaliaseSynonyms: PAH Deficiency, PAH-gene related phenylketonuriaHomatropine
go.drugbank.com/drugs/DB11181ApprovedHomatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. … It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions.
Cefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnAs part of its drug class, it shares structural properties to [cefalexin] as well as its activity spectrum. It was used in Italy but has since been withdrawn.
Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigational[L41900] It is used as monotherapy or in combination with other drugs, such as corticosteroids. … [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous injection. It was first approved by the FDA in 2017.
Difenoxin
go.drugbank.com/drugs/DB01501ApprovedIllicitDifenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. … However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse.
Tralokinumab
go.drugbank.com/drugs/DB12169ApprovedInvestigational[A242432] It is estimated to affect up to 20% of adults and children worldwide, and is frequently associated with other atopic conditions such as asthma or allergic rhinitis. … Tralokinumab was first approved for the treatment of atopic dermatitis by the EMA in June 2021, under the brand name Adtralza (Leo Pharma), and was subsequently approved in Canada in October 2021 and the
Copper oxodotreotide Cu-64
go.drugbank.com/drugs/DB15873ApprovedCopper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over <sup>68</sup>Ga-labeled somatostatin analogs for positron emission tomography (PET). … Further, PET using Copper Cu 64 dotatate has been found to perform better than the current gold standard of single-photon emission computed tomography (SPECT) using 111In-DTPA-octreotide.
Fexinidazole
go.drugbank.com/drugs/DB12265ApprovedHuman African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by _T. brucei gambiense_ and _T. brucei rhodesiense_, remains a moderate risk (>1/10,000 inhabitants per … [A237555, L35940] It is currently marketed by Sanofi-Aventis.[L35940]
Ecamsule
go.drugbank.com/drugs/DB09534ApprovedEcamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only in a few products manufactured by L'Oreal. … It is a benzylidene camphor derivative, many of which are known for their excellent photostability.
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