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Deslanoside
go.drugbank.com/drugs/DB01078ApprovedA cardiotonic glycoside from the leaves of Digitalis lanata.
Categories: Compounds used in a research, industrial, or household settingMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalclinical trials to be an inhibitor of Tau protein aggregation. … Its use as an urinary tract antiseptic has also been investigated.
Mixtures: Uro-L, UR N-C Urinary AntisepticCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesMitapivat
go.drugbank.com/drugs/DB16236ApprovedInvestigationalMitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. … [A245478] On February 17, 2022, the FDA approved mitapivat as the first disease-modifying treatment for hemolytic anemia in adults with pyruvate kinase (PK) deficiency, a rare, inherited disorder leading
Synonyms: Pkr-in-1Dornase alfa
go.drugbank.com/drugs/DB00003ApprovedInvestigationalDornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA.
Products: PULMOZYME 2.500 E./2,5 ml - Lösung für einen VerneblerEugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalIt has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. … Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.
Categories: Compounds used in a research, industrial, or household settingChlorothiazide
go.drugbank.com/drugs/DB00880ApprovedInvestigationalVet approvedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Debrisoquine
go.drugbank.com/drugs/DB04840ApprovedAn adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. … They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Milnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigationalfor noradrenaline reuptake inhibition - which is potentially a point of interest given the plausible proposal that noradrenaline plays an important role in the mitigation of pain signals in the descending … Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment
Isosulfan blue
go.drugbank.com/drugs/DB09136ApprovedInvestigationalCategories: Compounds used in a research, industrial, or household settingAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approved[F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population … M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil.
Synonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A, -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINECategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index