Search
Dosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalDosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits anticholinergic, antihistamine and central sedative properties [L882]. … Its hydrochloride form is a common active ingredient in different drug formulations.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: ESPIN CAPSULE 25 mgPenbutolol
go.drugbank.com/drugs/DB01359ApprovedInvestigationalWithdrawnPenbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. … Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: BETAPRESSİN 40 MG FİLM TABLET, 30 TABLETFidaxomicin
go.drugbank.com/drugs/DB08874ApprovedInvestigational[L11575] Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. … [A190492] Unlike vancomycin, however, fidaxomicin has a negligible effect on normal colonic microflora.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: DİFİCLİR 200 MG FİLM KAPLI TABLET, 20 ADETLapatinib
go.drugbank.com/drugs/DB01259ApprovedInvestigationalLapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. … Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: TYKERB 250 MG FILM TABLET, 70 ADET, LAPATINIB EGGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigationalGilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. … This drug was approved after being designed as an orphan drug with a fast track and priority review status.[L4830]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADETLindane
go.drugbank.com/drugs/DB00431ApprovedWithdrawnAn organochlorine insecticide that has been used as a pediculicide and a scabicide. … In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical
Categories: Compounds used in a research, industrial, or household settingProducts: Hexit Shampoo 1.0%Cobalt
go.drugbank.com/drugs/DB14574ApprovedWithdrawnA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments.
Products: Cobalt - Liq. 29.5 Mcg/mlCopper gluconate
go.drugbank.com/drugs/DB11246ApprovedInvestigationalCopper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. … According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005
Mixtures: Vitamin A C E W.niacinam.beta Car.and Min.Products: Copper (gluconate) 2 Mg TabletsChloramphenicol succinate
go.drugbank.com/drugs/DB07565Approved[A192987] Chloramphenicol is a bacteriostatic antibiotic.[A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: GEMYSETIN SÜKSİNAT 1G I.M./ I.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 100 FLAKON, SUMICLORAN ® 1 G INYECTABLESulfate ion
go.drugbank.com/drugs/DB14546InvestigationalMixtures: VAMIN 14 IV AMINOASIT SOLÜSYONU, 500 MLProducts: Loa Freedom S, Loa New-freedom S